(define (problem Pathways-09)
(:domain Pathways-ComplexPreferences)
(:objects
	Wee1 - simple
	SL1 - simple
	Raf1 - simple
	pRbp2 - simple
	pRbp1-E2F4p1-DP12 - simple
	pRb - simple
	Plk1 - simple
	PCNA - simple
	p53 - simple
	p16 - simple
	p130-E2F5p1-DP12 - simple
	p130-E2F4p1-DP12 - simple
	p130 - simple
	Myt1 - simple
	m1433 - simple
	Jun - simple
	HDAC1 - simple
	HBP1 - simple
	gE-c - simple
	E2F6 - simple
	E2F5 - simple
	E2F4 - simple
	E2F3 - simple
	E2F2 - simple
	E2F13p1-DP12p1 - simple
	E2F13p1-DP12 - simple
	E2F13-DP12p1 - simple
	E2F13-DP12 - simple
	E2F1 - simple
	DP12 - simple
	cycH - simple
	cycB - simple
	C-TAK1 - simple
	cks1 - simple
	CEBP - simple
	cdk7 - simple
	cdk46p3-cycDp1 - simple
	cdk46p3-cycD - simple
	cdk46p1 - simple
	cdk2p2-cycB - simple
	cdk2p1 - simple
	cdk2-cycB - simple
	cdk2 - simple
	cdk1p1p2 - simple
	cdc25C - simple
	c-Abl - simple
	APC - simple
	AP2 - simple
	AP2-gE-c - complex
	c-Abl-pRb - complex
	c-Abl-pRbp1 - complex
	c-Abl-pRbp1p2 - complex
	c-Abl-pRbp2 - complex
	cdk1-cks1 - complex
	cdk1-Gadd45 - complex
	cdk1p1-cks1 - complex
	cdk1p1-Gadd45 - complex
	cdk1p1 - complex
	cdk1p1p2-cks1 - complex
	cdk1p1p2-Gadd45 - complex
	cdk1p1p2p3-cks1 - complex
	cdk1p1p2p3-Gadd45 - complex
	cdk1p1p2p3 - complex
	cdk1p1p3-cks1 - complex
	cdk1p1p3-Gadd45 - complex
	cdk1p1p3 - complex
	cdk1 - complex
	cdk1p2-cks1 - complex
	cdk1p2-Gadd45 - complex
	cdk1p2 - complex
	cdk1p2p3-cks1 - complex
	cdc25Cp1 - complex
	cdk1p1p2p3-cycB - complex
	cdk1p2p3-Gadd45 - complex
	cdk1p2p3 - complex
	cdk1p3-cks1 - complex
	cdk1p1p3-cycB - complex
	cdk1p2p3-cycB - complex
	cdk1p3-Gadd45 - complex
	cdk1p3 - complex
	cdk2-cks1 - complex
	cdk2p1-cycB - complex
	cdk2p1-cks1 - complex
	cdk2p1p2-cks1 - complex
	cdk2p1p2 - complex
	cdk2p2-cks1 - complex
	cdk2p1p2-cycB - complex
	cdk2p2 - complex
	cdk7-cycH - complex
	cdk7p1-cycH - complex
	CEBP-pRb - complex
	CEBP-pRbp1 - complex
	CEBP-pRbp1p2 - complex
	CEBP-pRbp2 - complex
	APCp1 - complex
	E2F1-DP12 - complex
	E2F2-DP12 - complex
	E2F3-DP12 - complex
	E2F6-DP12 - complex
	HBP1-p130 - complex
	HDAC1-p130-E2F4-DP12 - complex
	HDAC1-p130-E2F5-DP12 - complex
	HDAC1-pRb-E2F13-DP12 - complex
	HDAC1-pRb-E2F13-DP12p1 - complex
	HDAC1-pRb-E2F13p1-DP12 - complex
	HDAC1-pRb-E2F13p1-DP12p1 - complex
	HDAC1-pRb-E2F4-DP12 - complex
	Jun-c-Fos - complex
	m1433-cdc25Cp1p2 - complex
	cdc25Cp1p2 - complex
	m1433-cdc25Cp2 - complex
	cdc25Cp2 - complex
	Mdm2-E2F13-DP12 - complex
	Mdm2-E2F13-DP12p1 - complex
	Mdm2-E2F13p1-DP12 - complex
	Mdm2-E2F13p1-DP12p1 - complex
	Mdm2-pRb - complex
	Mdm2-pRbp1 - complex
	Mdm2-pRbp1p2 - complex
	Mdm2-pRbp2 - complex
	E2F5-DP12 - complex
	p16-cdk46p1 - complex
	p16-cdk46p1p2 - complex
	cdk46p1p2 - complex
	p16-cdk7 - complex
	p16-cdk7p1 - complex
	cdk7p1 - complex
	p21-Gadd45 - complex
	p53-DP12 - complex
	Mdm2 - complex
	PCNA-Gadd45 - complex
	Gadd45 - complex
	PCNA-p21 - complex
	p21 - complex
	pRb-AP2-gE-c - complex
	pRb-AP2 - complex
	pRb-Jun-c-Fos - complex
	pRb-Jun - complex
	pRbp1-AP2-gE-c - complex
	pRbp1-AP2 - complex
	E2F4-DP12 - complex
	pRbp1-Jun-c-Fos - complex
	pRbp1-Jun - complex
	pRbp1 - complex
	pRbp1p2-AP2-gE-c - complex
	pRbp1p2-AP2 - complex
	pRbp1p2-Jun-c-Fos - complex
	pRbp1p2-Jun - complex
	Ecadherin - complex
	pRbp2-AP2-gE-c - complex
	pRbp2-AP2 - complex
	pRbp1p2 - complex
	pRbp2-Jun-c-Fos - complex
	c-Fos - complex
	pRbp2-Jun - complex
	Raf1-p130-E2F4-DP12 - complex
	p130-E2F4-DP12 - complex
	Raf1-p130-E2F4p1-DP12 - complex
	Raf1-p130-E2F5-DP12 - complex
	p130-E2F5-DP12 - complex
	Raf1-p130-E2F5p1-DP12 - complex
	Raf1-pRb-E2F13-DP12p1 - complex
	pRb-E2F13-DP12p1 - complex
	Raf1-pRb-E2F13-DP12 - complex
	pRb-E2F13-DP12 - complex
	Raf1-pRb-E2F13p1-DP12p1 - complex
	pRb-E2F13p1-DP12p1 - complex
	Raf1-pRb-E2F13p1-DP12 - complex
	pRb-E2F13p1-DP12 - complex
	Raf1-pRb-E2F4-DP12 - complex
	pRb-E2F4-DP12 - complex
	Raf1-pRbp1-E2F13-DP12p1 - complex
	pRbp1-E2F13-DP12p1 - complex
	Raf1-pRbp1-E2F13-DP12 - complex
	pRbp1-E2F13-DP12 - complex
	Raf1-pRbp1-E2F13p1-DP12p1 - complex
	pRbp1-E2F13p1-DP12p1 - complex
	Raf1-pRbp1-E2F13p1-DP12 - complex
	pRbp1-E2F13p1-DP12 - complex
	Raf1-pRbp1-E2F4-DP12 - complex
	pRbp1-E2F4-DP12 - complex
	Raf1-pRbp1-E2F4p1-DP12 - complex
	SL1p1 - complex
	Wee1p1 - complex
	cdk1p3-cycB - complex)


(:init
	(possible Wee1)
	(= (available Wee1) 0)
	(possible SL1)
	(= (available SL1) 0)
	(possible Raf1)
	(= (available Raf1) 0)
	(possible pRbp2)
	(= (available pRbp2) 0)
	(possible pRbp1-E2F4p1-DP12)
	(= (available pRbp1-E2F4p1-DP12) 0)
	(possible pRb)
	(= (available pRb) 0)
	(possible Plk1)
	(= (available Plk1) 0)
	(possible PCNA)
	(= (available PCNA) 0)
	(possible p53)
	(= (available p53) 0)
	(possible p16)
	(= (available p16) 0)
	(possible p130-E2F5p1-DP12)
	(= (available p130-E2F5p1-DP12) 0)
	(possible p130-E2F4p1-DP12)
	(= (available p130-E2F4p1-DP12) 0)
	(possible p130)
	(= (available p130) 0)
	(possible Myt1)
	(= (available Myt1) 0)
	(possible m1433)
	(= (available m1433) 0)
	(possible Jun)
	(= (available Jun) 0)
	(possible HDAC1)
	(= (available HDAC1) 0)
	(possible HBP1)
	(= (available HBP1) 0)
	(possible gE-c)
	(= (available gE-c) 0)
	(possible E2F6)
	(= (available E2F6) 0)
	(possible E2F5)
	(= (available E2F5) 0)
	(possible E2F4)
	(= (available E2F4) 0)
	(possible E2F3)
	(= (available E2F3) 0)
	(possible E2F2)
	(= (available E2F2) 0)
	(possible E2F13p1-DP12p1)
	(= (available E2F13p1-DP12p1) 0)
	(possible E2F13p1-DP12)
	(= (available E2F13p1-DP12) 0)
	(possible E2F13-DP12p1)
	(= (available E2F13-DP12p1) 0)
	(possible E2F13-DP12)
	(= (available E2F13-DP12) 0)
	(possible E2F1)
	(= (available E2F1) 0)
	(possible DP12)
	(= (available DP12) 0)
	(possible cycH)
	(= (available cycH) 0)
	(possible cycB)
	(= (available cycB) 0)
	(possible C-TAK1)
	(= (available C-TAK1) 0)
	(possible cks1)
	(= (available cks1) 0)
	(possible CEBP)
	(= (available CEBP) 0)
	(possible cdk7)
	(= (available cdk7) 0)
	(possible cdk46p3-cycDp1)
	(= (available cdk46p3-cycDp1) 0)
	(possible cdk46p3-cycD)
	(= (available cdk46p3-cycD) 0)
	(possible cdk46p1)
	(= (available cdk46p1) 0)
	(possible cdk2p2-cycB)
	(= (available cdk2p2-cycB) 0)
	(possible cdk2p1)
	(= (available cdk2p1) 0)
	(possible cdk2-cycB)
	(= (available cdk2-cycB) 0)
	(possible cdk2)
	(= (available cdk2) 0)
	(possible cdk1p1p2)
	(= (available cdk1p1p2) 0)
	(possible cdc25C)
	(= (available cdc25C) 0)
	(possible c-Abl)
	(= (available c-Abl) 0)
	(possible APC)
	(= (available APC) 0)
	(possible AP2)
	(= (available AP2) 0)
	(= (available AP2-gE-c) 0)
	(= (available c-Abl-pRb) 0)
	(= (available c-Abl-pRbp1) 0)
	(= (available c-Abl-pRbp1p2) 0)
	(= (available c-Abl-pRbp2) 0)
	(= (available cdk1-cks1) 0)
	(= (available cdk1-Gadd45) 0)
	(= (available cdk1p1-cks1) 0)
	(= (available cdk1p1-Gadd45) 0)
	(= (available cdk1p1) 0)
	(= (available cdk1p1p2-cks1) 0)
	(= (available cdk1p1p2-Gadd45) 0)
	(= (available cdk1p1p2p3-cks1) 0)
	(= (available cdk1p1p2p3-Gadd45) 0)
	(= (available cdk1p1p2p3) 0)
	(= (available cdk1p1p3-cks1) 0)
	(= (available cdk1p1p3-Gadd45) 0)
	(= (available cdk1p1p3) 0)
	(= (available cdk1) 0)
	(= (available cdk1p2-cks1) 0)
	(= (available cdk1p2-Gadd45) 0)
	(= (available cdk1p2) 0)
	(= (available cdk1p2p3-cks1) 0)
	(= (available cdc25Cp1) 0)
	(= (available cdk1p1p2p3-cycB) 0)
	(= (available cdk1p2p3-Gadd45) 0)
	(= (available cdk1p2p3) 0)
	(= (available cdk1p3-cks1) 0)
	(= (available cdk1p1p3-cycB) 0)
	(= (available cdk1p2p3-cycB) 0)
	(= (available cdk1p3-Gadd45) 0)
	(= (available cdk1p3) 0)
	(= (available cdk2-cks1) 0)
	(= (available cdk2p1-cycB) 0)
	(= (available cdk2p1-cks1) 0)
	(= (available cdk2p1p2-cks1) 0)
	(= (available cdk2p1p2) 0)
	(= (available cdk2p2-cks1) 0)
	(= (available cdk2p1p2-cycB) 0)
	(= (available cdk2p2) 0)
	(= (available cdk7-cycH) 0)
	(= (available cdk7p1-cycH) 0)
	(= (available CEBP-pRb) 0)
	(= (available CEBP-pRbp1) 0)
	(= (available CEBP-pRbp1p2) 0)
	(= (available CEBP-pRbp2) 0)
	(= (available APCp1) 0)
	(= (available E2F1-DP12) 0)
	(= (available E2F2-DP12) 0)
	(= (available E2F3-DP12) 0)
	(= (available E2F6-DP12) 0)
	(= (available HBP1-p130) 0)
	(= (available HDAC1-p130-E2F4-DP12) 0)
	(= (available HDAC1-p130-E2F5-DP12) 0)
	(= (available HDAC1-pRb-E2F13-DP12) 0)
	(= (available HDAC1-pRb-E2F13-DP12p1) 0)
	(= (available HDAC1-pRb-E2F13p1-DP12) 0)
	(= (available HDAC1-pRb-E2F13p1-DP12p1) 0)
	(= (available HDAC1-pRb-E2F4-DP12) 0)
	(= (available Jun-c-Fos) 0)
	(= (available m1433-cdc25Cp1p2) 0)
	(= (available cdc25Cp1p2) 0)
	(= (available m1433-cdc25Cp2) 0)
	(= (available cdc25Cp2) 0)
	(= (available Mdm2-E2F13-DP12) 0)
	(= (available Mdm2-E2F13-DP12p1) 0)
	(= (available Mdm2-E2F13p1-DP12) 0)
	(= (available Mdm2-E2F13p1-DP12p1) 0)
	(= (available Mdm2-pRb) 0)
	(= (available Mdm2-pRbp1) 0)
	(= (available Mdm2-pRbp1p2) 0)
	(= (available Mdm2-pRbp2) 0)
	(= (available E2F5-DP12) 0)
	(= (available p16-cdk46p1) 0)
	(= (available p16-cdk46p1p2) 0)
	(= (available cdk46p1p2) 0)
	(= (available p16-cdk7) 0)
	(= (available p16-cdk7p1) 0)
	(= (available cdk7p1) 0)
	(= (available p21-Gadd45) 0)
	(= (available p53-DP12) 0)
	(= (available Mdm2) 0)
	(= (available PCNA-Gadd45) 0)
	(= (available Gadd45) 0)
	(= (available PCNA-p21) 0)
	(= (available p21) 0)
	(= (available pRb-AP2-gE-c) 0)
	(= (available pRb-AP2) 0)
	(= (available pRb-Jun-c-Fos) 0)
	(= (available pRb-Jun) 0)
	(= (available pRbp1-AP2-gE-c) 0)
	(= (available pRbp1-AP2) 0)
	(= (available E2F4-DP12) 0)
	(= (available pRbp1-Jun-c-Fos) 0)
	(= (available pRbp1-Jun) 0)
	(= (available pRbp1) 0)
	(= (available pRbp1p2-AP2-gE-c) 0)
	(= (available pRbp1p2-AP2) 0)
	(= (available pRbp1p2-Jun-c-Fos) 0)
	(= (available pRbp1p2-Jun) 0)
	(= (available Ecadherin) 0)
	(= (available pRbp2-AP2-gE-c) 0)
	(= (available pRbp2-AP2) 0)
	(= (available pRbp1p2) 0)
	(= (available pRbp2-Jun-c-Fos) 0)
	(= (available c-Fos) 0)
	(= (available pRbp2-Jun) 0)
	(= (available Raf1-p130-E2F4-DP12) 0)
	(= (available p130-E2F4-DP12) 0)
	(= (available Raf1-p130-E2F4p1-DP12) 0)
	(= (available Raf1-p130-E2F5-DP12) 0)
	(= (available p130-E2F5-DP12) 0)
	(= (available Raf1-p130-E2F5p1-DP12) 0)
	(= (available Raf1-pRb-E2F13-DP12p1) 0)
	(= (available pRb-E2F13-DP12p1) 0)
	(= (available Raf1-pRb-E2F13-DP12) 0)
	(= (available pRb-E2F13-DP12) 0)
	(= (available Raf1-pRb-E2F13p1-DP12p1) 0)
	(= (available pRb-E2F13p1-DP12p1) 0)
	(= (available Raf1-pRb-E2F13p1-DP12) 0)
	(= (available pRb-E2F13p1-DP12) 0)
	(= (available Raf1-pRb-E2F4-DP12) 0)
	(= (available pRb-E2F4-DP12) 0)
	(= (available Raf1-pRbp1-E2F13-DP12p1) 0)
	(= (available pRbp1-E2F13-DP12p1) 0)
	(= (available Raf1-pRbp1-E2F13-DP12) 0)
	(= (available pRbp1-E2F13-DP12) 0)
	(= (available Raf1-pRbp1-E2F13p1-DP12p1) 0)
	(= (available pRbp1-E2F13p1-DP12p1) 0)
	(= (available Raf1-pRbp1-E2F13p1-DP12) 0)
	(= (available pRbp1-E2F13p1-DP12) 0)
	(= (available Raf1-pRbp1-E2F4-DP12) 0)
	(= (available pRbp1-E2F4-DP12) 0)
	(= (available Raf1-pRbp1-E2F4p1-DP12) 0)
	(= (available SL1p1) 0)
	(= (available Wee1p1) 0)
	(= (available cdk1p3-cycB) 0)
	(association-reaction AP2 gE-c AP2-gE-c)
	(= (need-for-association AP2 gE-c AP2-gE-c) 2)
	(= (need-for-association gE-c AP2 AP2-gE-c) 2)
	(= (prod-by-association AP2 gE-c AP2-gE-c) 4)
	(synthesis-reaction AP2-gE-c Ecadherin) 
	(= (need-for-synthesis AP2-gE-c Ecadherin) 3)
	(= (prod-by-synthesis AP2-gE-c Ecadherin) 2)
	(catalyzed-association-reaction APC Plk1 APCp1)
	(= (need-for-catalyzed-association APC Plk1 APCp1) 1)
	(= (need-for-catalyzed-association Plk1 APC APCp1) 4)
	(= (prod-by-catalyzed-association APC Plk1 APCp1) 3)
	(association-reaction c-Abl pRb c-Abl-pRb)
	(= (need-for-association c-Abl pRb c-Abl-pRb) 4)
	(= (need-for-association pRb c-Abl c-Abl-pRb) 2)
	(= (prod-by-association c-Abl pRb c-Abl-pRb) 2)
	(association-reaction c-Abl pRbp1 c-Abl-pRbp1)
	(= (need-for-association c-Abl pRbp1 c-Abl-pRbp1) 2)
	(= (need-for-association pRbp1 c-Abl c-Abl-pRbp1) 2)
	(= (prod-by-association c-Abl pRbp1 c-Abl-pRbp1) 2)
	(association-reaction c-Abl pRbp1p2 c-Abl-pRbp1p2)
	(= (need-for-association c-Abl pRbp1p2 c-Abl-pRbp1p2) 4)
	(= (need-for-association pRbp1p2 c-Abl c-Abl-pRbp1p2) 1)
	(= (prod-by-association c-Abl pRbp1p2 c-Abl-pRbp1p2) 3)
	(association-reaction c-Abl pRbp2 c-Abl-pRbp2)
	(= (need-for-association c-Abl pRbp2 c-Abl-pRbp2) 3)
	(= (need-for-association pRbp2 c-Abl c-Abl-pRbp2) 4)
	(= (prod-by-association c-Abl pRbp2 c-Abl-pRbp2) 2)
	(catalyzed-association-reaction cdc25C cdk1p3-cycB cdc25Cp1)
	(= (need-for-catalyzed-association cdc25C cdk1p3-cycB cdc25Cp1) 3)
	(= (need-for-catalyzed-association cdk1p3-cycB cdc25C cdc25Cp1) 2)
	(= (prod-by-catalyzed-association cdc25C cdk1p3-cycB cdc25Cp1) 3)
	(catalyzed-association-reaction cdc25C C-TAK1 cdc25Cp2)
	(= (need-for-catalyzed-association cdc25C C-TAK1 cdc25Cp2) 3)
	(= (need-for-catalyzed-association C-TAK1 cdc25C cdc25Cp2) 1)
	(= (prod-by-catalyzed-association cdc25C C-TAK1 cdc25Cp2) 3)
	(catalyzed-association-reaction cdc25Cp1 C-TAK1 cdc25Cp1p2)
	(= (need-for-catalyzed-association cdc25Cp1 C-TAK1 cdc25Cp1p2) 2)
	(= (need-for-catalyzed-association C-TAK1 cdc25Cp1 cdc25Cp1p2) 2)
	(= (prod-by-catalyzed-association cdc25Cp1 C-TAK1 cdc25Cp1p2) 1)
	(catalyzed-association-reaction cdc25Cp2 cdk1p3-cycB cdc25Cp1p2)
	(= (need-for-catalyzed-association cdc25Cp2 cdk1p3-cycB cdc25Cp1p2) 3)
	(= (need-for-catalyzed-association cdk1p3-cycB cdc25Cp2 cdc25Cp1p2) 4)
	(= (prod-by-catalyzed-association cdc25Cp2 cdk1p3-cycB cdc25Cp1p2) 2)
	(catalyzed-association-reaction cdc25Cp2 Plk1 cdc25Cp1p2)
	(= (need-for-catalyzed-association cdc25Cp2 Plk1 cdc25Cp1p2) 1)
	(= (need-for-catalyzed-association Plk1 cdc25Cp2 cdc25Cp1p2) 3)
	(= (prod-by-catalyzed-association cdc25Cp2 Plk1 cdc25Cp1p2) 1)
	(catalyzed-association-reaction cdc25C Plk1 cdc25Cp1)
	(= (need-for-catalyzed-association cdc25C Plk1 cdc25Cp1) 2)
	(= (need-for-catalyzed-association Plk1 cdc25C cdc25Cp1) 3)
	(= (prod-by-catalyzed-association cdc25C Plk1 cdc25Cp1) 4)
	(catalyzed-association-reaction cdk1 cdk7-cycH cdk1p3)
	(= (need-for-catalyzed-association cdk1 cdk7-cycH cdk1p3) 4)
	(= (need-for-catalyzed-association cdk7-cycH cdk1 cdk1p3) 2)
	(= (prod-by-catalyzed-association cdk1 cdk7-cycH cdk1p3) 1)
	(association-reaction cdk1 cks1 cdk1-cks1)
	(= (need-for-association cdk1 cks1 cdk1-cks1) 1)
	(= (need-for-association cks1 cdk1 cdk1-cks1) 3)
	(= (prod-by-association cdk1 cks1 cdk1-cks1) 3)
	(association-reaction cdk1 Gadd45 cdk1-Gadd45)
	(= (need-for-association cdk1 Gadd45 cdk1-Gadd45) 2)
	(= (need-for-association Gadd45 cdk1 cdk1-Gadd45) 3)
	(= (prod-by-association cdk1 Gadd45 cdk1-Gadd45) 3)
	(catalyzed-association-reaction cdk1p1 cdc25Cp1 cdk1)
	(= (need-for-catalyzed-association cdk1p1 cdc25Cp1 cdk1) 4)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1 cdk1) 1)
	(= (prod-by-catalyzed-association cdk1p1 cdc25Cp1 cdk1) 2)
	(catalyzed-association-reaction cdk1p1 cdc25Cp1p2 cdk1)
	(= (need-for-catalyzed-association cdk1p1 cdc25Cp1p2 cdk1) 1)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1 cdk1) 4)
	(= (prod-by-catalyzed-association cdk1p1 cdc25Cp1p2 cdk1) 3)
	(catalyzed-association-reaction cdk1p1 cdk7-cycH cdk1p1p3)
	(= (need-for-catalyzed-association cdk1p1 cdk7-cycH cdk1p1p3) 4)
	(= (need-for-catalyzed-association cdk7-cycH cdk1p1 cdk1p1p3) 2)
	(= (prod-by-catalyzed-association cdk1p1 cdk7-cycH cdk1p1p3) 3)
	(association-reaction cdk1p1 cks1 cdk1p1-cks1)
	(= (need-for-association cdk1p1 cks1 cdk1p1-cks1) 2)
	(= (need-for-association cks1 cdk1p1 cdk1p1-cks1) 3)
	(= (prod-by-association cdk1p1 cks1 cdk1p1-cks1) 4)
	(association-reaction cdk1p1 Gadd45 cdk1p1-Gadd45)
	(= (need-for-association cdk1p1 Gadd45 cdk1p1-Gadd45) 2)
	(= (need-for-association Gadd45 cdk1p1 cdk1p1-Gadd45) 2)
	(= (prod-by-association cdk1p1 Gadd45 cdk1p1-Gadd45) 3)
	(catalyzed-association-reaction cdk1p1p2 cdc25Cp1 cdk1p1)
	(= (need-for-catalyzed-association cdk1p1p2 cdc25Cp1 cdk1p1) 4)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p2 cdk1p1) 2)
	(= (prod-by-catalyzed-association cdk1p1p2 cdc25Cp1 cdk1p1) 2)
	(catalyzed-association-reaction cdk1p1p2 cdc25Cp1 cdk1p2)
	(= (need-for-catalyzed-association cdk1p1p2 cdc25Cp1 cdk1p2) 4)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p2 cdk1p2) 3)
	(= (prod-by-catalyzed-association cdk1p1p2 cdc25Cp1 cdk1p2) 4)
	(catalyzed-association-reaction cdk1p1p2 cdc25Cp1p2 cdk1p1)
	(= (need-for-catalyzed-association cdk1p1p2 cdc25Cp1p2 cdk1p1) 3)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p2 cdk1p1) 2)
	(= (prod-by-catalyzed-association cdk1p1p2 cdc25Cp1p2 cdk1p1) 2)
	(catalyzed-association-reaction cdk1p1p2 cdc25Cp1p2 cdk1p2)
	(= (need-for-catalyzed-association cdk1p1p2 cdc25Cp1p2 cdk1p2) 3)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p2 cdk1p2) 2)
	(= (prod-by-catalyzed-association cdk1p1p2 cdc25Cp1p2 cdk1p2) 4)
	(catalyzed-association-reaction cdk1p1p2 cdk7-cycH cdk1p1p2p3)
	(= (need-for-catalyzed-association cdk1p1p2 cdk7-cycH cdk1p1p2p3) 1)
	(= (need-for-catalyzed-association cdk7-cycH cdk1p1p2 cdk1p1p2p3) 3)
	(= (prod-by-catalyzed-association cdk1p1p2 cdk7-cycH cdk1p1p2p3) 2)
	(association-reaction cdk1p1p2 cks1 cdk1p1p2-cks1)
	(= (need-for-association cdk1p1p2 cks1 cdk1p1p2-cks1) 3)
	(= (need-for-association cks1 cdk1p1p2 cdk1p1p2-cks1) 2)
	(= (prod-by-association cdk1p1p2 cks1 cdk1p1p2-cks1) 3)
	(association-reaction cdk1p1p2 Gadd45 cdk1p1p2-Gadd45)
	(= (need-for-association cdk1p1p2 Gadd45 cdk1p1p2-Gadd45) 4)
	(= (need-for-association Gadd45 cdk1p1p2 cdk1p1p2-Gadd45) 3)
	(= (prod-by-association cdk1p1p2 Gadd45 cdk1p1p2-Gadd45) 2)
	(catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1 cdk1p1p3)
	(= (need-for-catalyzed-association cdk1p1p2p3 cdc25Cp1 cdk1p1p3) 2)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p2p3 cdk1p1p3) 2)
	(= (prod-by-catalyzed-association cdk1p1p2p3 cdc25Cp1 cdk1p1p3) 3)
	(catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1 cdk1p2p3)
	(= (need-for-catalyzed-association cdk1p1p2p3 cdc25Cp1 cdk1p2p3) 4)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p2p3 cdk1p2p3) 3)
	(= (prod-by-catalyzed-association cdk1p1p2p3 cdc25Cp1 cdk1p2p3) 2)
	(catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1p2 cdk1p1p3)
	(= (need-for-catalyzed-association cdk1p1p2p3 cdc25Cp1p2 cdk1p1p3) 4)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p2p3 cdk1p1p3) 1)
	(= (prod-by-catalyzed-association cdk1p1p2p3 cdc25Cp1p2 cdk1p1p3) 3)
	(catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1p2 cdk1p2p3)
	(= (need-for-catalyzed-association cdk1p1p2p3 cdc25Cp1p2 cdk1p2p3) 2)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p2p3 cdk1p2p3) 4)
	(= (prod-by-catalyzed-association cdk1p1p2p3 cdc25Cp1p2 cdk1p2p3) 4)
	(association-reaction cdk1p1p2p3 cks1 cdk1p1p2p3-cks1)
	(= (need-for-association cdk1p1p2p3 cks1 cdk1p1p2p3-cks1) 3)
	(= (need-for-association cks1 cdk1p1p2p3 cdk1p1p2p3-cks1) 3)
	(= (prod-by-association cdk1p1p2p3 cks1 cdk1p1p2p3-cks1) 2)
	(catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1 cdk1p1p3-cycB)
	(= (need-for-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1 cdk1p1p3-cycB) 3)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p2p3-cycB cdk1p1p3-cycB) 1)
	(= (prod-by-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1 cdk1p1p3-cycB) 3)
	(catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1 cdk1p2p3-cycB)
	(= (need-for-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1 cdk1p2p3-cycB) 4)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p2p3-cycB cdk1p2p3-cycB) 3)
	(= (prod-by-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1 cdk1p2p3-cycB) 4)
	(catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p1p3-cycB)
	(= (need-for-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p1p3-cycB) 3)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p2p3-cycB cdk1p1p3-cycB) 4)
	(= (prod-by-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p1p3-cycB) 2)
	(catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p2p3-cycB)
	(= (need-for-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p2p3-cycB) 1)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p2p3-cycB cdk1p2p3-cycB) 2)
	(= (prod-by-catalyzed-association cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p2p3-cycB) 3)
	(association-reaction cdk1p1p2p3 cycB cdk1p1p2p3-cycB)
	(= (need-for-association cdk1p1p2p3 cycB cdk1p1p2p3-cycB) 3)
	(= (need-for-association cycB cdk1p1p2p3 cdk1p1p2p3-cycB) 2)
	(= (prod-by-association cdk1p1p2p3 cycB cdk1p1p2p3-cycB) 1)
	(association-reaction cdk1p1p2p3 Gadd45 cdk1p1p2p3-Gadd45)
	(= (need-for-association cdk1p1p2p3 Gadd45 cdk1p1p2p3-Gadd45) 4)
	(= (need-for-association Gadd45 cdk1p1p2p3 cdk1p1p2p3-Gadd45) 3)
	(= (prod-by-association cdk1p1p2p3 Gadd45 cdk1p1p2p3-Gadd45) 2)
	(catalyzed-association-reaction cdk1p1p3 cdc25Cp1 cdk1p3)
	(= (need-for-catalyzed-association cdk1p1p3 cdc25Cp1 cdk1p3) 2)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p3 cdk1p3) 3)
	(= (prod-by-catalyzed-association cdk1p1p3 cdc25Cp1 cdk1p3) 1)
	(catalyzed-association-reaction cdk1p1p3 cdc25Cp1p2 cdk1p3)
	(= (need-for-catalyzed-association cdk1p1p3 cdc25Cp1p2 cdk1p3) 3)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p3 cdk1p3) 2)
	(= (prod-by-catalyzed-association cdk1p1p3 cdc25Cp1p2 cdk1p3) 1)
	(association-reaction cdk1p1p3 cks1 cdk1p1p3-cks1)
	(= (need-for-association cdk1p1p3 cks1 cdk1p1p3-cks1) 1)
	(= (need-for-association cks1 cdk1p1p3 cdk1p1p3-cks1) 3)
	(= (prod-by-association cdk1p1p3 cks1 cdk1p1p3-cks1) 4)
	(catalyzed-association-reaction cdk1p1p3-cycB cdc25Cp1 cdk1p3-cycB)
	(= (need-for-catalyzed-association cdk1p1p3-cycB cdc25Cp1 cdk1p3-cycB) 4)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p1p3-cycB cdk1p3-cycB) 2)
	(= (prod-by-catalyzed-association cdk1p1p3-cycB cdc25Cp1 cdk1p3-cycB) 2)
	(catalyzed-association-reaction cdk1p1p3-cycB cdc25Cp1p2 cdk1p3-cycB)
	(= (need-for-catalyzed-association cdk1p1p3-cycB cdc25Cp1p2 cdk1p3-cycB) 1)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p1p3-cycB cdk1p3-cycB) 4)
	(= (prod-by-catalyzed-association cdk1p1p3-cycB cdc25Cp1p2 cdk1p3-cycB) 2)
	(association-reaction cdk1p1p3 cycB cdk1p1p3-cycB)
	(= (need-for-association cdk1p1p3 cycB cdk1p1p3-cycB) 3)
	(= (need-for-association cycB cdk1p1p3 cdk1p1p3-cycB) 3)
	(= (prod-by-association cdk1p1p3 cycB cdk1p1p3-cycB) 4)
	(catalyzed-association-reaction cdk1p1p3-cycB Wee1 cdk1p1p2p3-cycB)
	(= (need-for-catalyzed-association cdk1p1p3-cycB Wee1 cdk1p1p2p3-cycB) 2)
	(= (need-for-catalyzed-association Wee1 cdk1p1p3-cycB cdk1p1p2p3-cycB) 1)
	(= (prod-by-catalyzed-association cdk1p1p3-cycB Wee1 cdk1p1p2p3-cycB) 3)
	(association-reaction cdk1p1p3 Gadd45 cdk1p1p3-Gadd45)
	(= (need-for-association cdk1p1p3 Gadd45 cdk1p1p3-Gadd45) 3)
	(= (need-for-association Gadd45 cdk1p1p3 cdk1p1p3-Gadd45) 1)
	(= (prod-by-association cdk1p1p3 Gadd45 cdk1p1p3-Gadd45) 1)
	(catalyzed-association-reaction cdk1p2 cdc25Cp1 cdk1)
	(= (need-for-catalyzed-association cdk1p2 cdc25Cp1 cdk1) 2)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p2 cdk1) 3)
	(= (prod-by-catalyzed-association cdk1p2 cdc25Cp1 cdk1) 2)
	(catalyzed-association-reaction cdk1p2 cdc25Cp1p2 cdk1)
	(= (need-for-catalyzed-association cdk1p2 cdc25Cp1p2 cdk1) 2)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p2 cdk1) 2)
	(= (prod-by-catalyzed-association cdk1p2 cdc25Cp1p2 cdk1) 4)
	(catalyzed-association-reaction cdk1p2 cdk7-cycH cdk1p2p3)
	(= (need-for-catalyzed-association cdk1p2 cdk7-cycH cdk1p2p3) 4)
	(= (need-for-catalyzed-association cdk7-cycH cdk1p2 cdk1p2p3) 4)
	(= (prod-by-catalyzed-association cdk1p2 cdk7-cycH cdk1p2p3) 2)
	(association-reaction cdk1p2 cks1 cdk1p2-cks1)
	(= (need-for-association cdk1p2 cks1 cdk1p2-cks1) 4)
	(= (need-for-association cks1 cdk1p2 cdk1p2-cks1) 2)
	(= (prod-by-association cdk1p2 cks1 cdk1p2-cks1) 3)
	(association-reaction cdk1p2 Gadd45 cdk1p2-Gadd45)
	(= (need-for-association cdk1p2 Gadd45 cdk1p2-Gadd45) 4)
	(= (need-for-association Gadd45 cdk1p2 cdk1p2-Gadd45) 3)
	(= (prod-by-association cdk1p2 Gadd45 cdk1p2-Gadd45) 2)
	(catalyzed-association-reaction cdk1p2p3 cdc25Cp1 cdk1p3)
	(= (need-for-catalyzed-association cdk1p2p3 cdc25Cp1 cdk1p3) 3)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p2p3 cdk1p3) 2)
	(= (prod-by-catalyzed-association cdk1p2p3 cdc25Cp1 cdk1p3) 3)
	(catalyzed-association-reaction cdk1p2p3 cdc25Cp1p2 cdk1p3)
	(= (need-for-catalyzed-association cdk1p2p3 cdc25Cp1p2 cdk1p3) 4)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p2p3 cdk1p3) 3)
	(= (prod-by-catalyzed-association cdk1p2p3 cdc25Cp1p2 cdk1p3) 2)
	(association-reaction cdk1p2p3 cks1 cdk1p2p3-cks1)
	(= (need-for-association cdk1p2p3 cks1 cdk1p2p3-cks1) 1)
	(= (need-for-association cks1 cdk1p2p3 cdk1p2p3-cks1) 1)
	(= (prod-by-association cdk1p2p3 cks1 cdk1p2p3-cks1) 4)
	(catalyzed-association-reaction cdk1p2p3-cycB cdc25Cp1 cdk1p3-cycB)
	(= (need-for-catalyzed-association cdk1p2p3-cycB cdc25Cp1 cdk1p3-cycB) 4)
	(= (need-for-catalyzed-association cdc25Cp1 cdk1p2p3-cycB cdk1p3-cycB) 3)
	(= (prod-by-catalyzed-association cdk1p2p3-cycB cdc25Cp1 cdk1p3-cycB) 4)
	(catalyzed-association-reaction cdk1p2p3-cycB cdc25Cp1p2 cdk1p3-cycB)
	(= (need-for-catalyzed-association cdk1p2p3-cycB cdc25Cp1p2 cdk1p3-cycB) 3)
	(= (need-for-catalyzed-association cdc25Cp1p2 cdk1p2p3-cycB cdk1p3-cycB) 1)
	(= (prod-by-catalyzed-association cdk1p2p3-cycB cdc25Cp1p2 cdk1p3-cycB) 1)
	(association-reaction cdk1p2p3 cycB cdk1p2p3-cycB)
	(= (need-for-association cdk1p2p3 cycB cdk1p2p3-cycB) 3)
	(= (need-for-association cycB cdk1p2p3 cdk1p2p3-cycB) 2)
	(= (prod-by-association cdk1p2p3 cycB cdk1p2p3-cycB) 3)
	(catalyzed-association-reaction cdk1p2p3-cycB Myt1 cdk1p1p2p3-cycB)
	(= (need-for-catalyzed-association cdk1p2p3-cycB Myt1 cdk1p1p2p3-cycB) 4)
	(= (need-for-catalyzed-association Myt1 cdk1p2p3-cycB cdk1p1p2p3-cycB) 4)
	(= (prod-by-catalyzed-association cdk1p2p3-cycB Myt1 cdk1p1p2p3-cycB) 1)
	(association-reaction cdk1p2p3 Gadd45 cdk1p2p3-Gadd45)
	(= (need-for-association cdk1p2p3 Gadd45 cdk1p2p3-Gadd45) 3)
	(= (need-for-association Gadd45 cdk1p2p3 cdk1p2p3-Gadd45) 3)
	(= (prod-by-association cdk1p2p3 Gadd45 cdk1p2p3-Gadd45) 4)
	(association-reaction cdk1p3 cks1 cdk1p3-cks1)
	(= (need-for-association cdk1p3 cks1 cdk1p3-cks1) 1)
	(= (need-for-association cks1 cdk1p3 cdk1p3-cks1) 2)
	(= (prod-by-association cdk1p3 cks1 cdk1p3-cks1) 1)
	(association-reaction cdk1p3 cycB cdk1p3-cycB)
	(= (need-for-association cdk1p3 cycB cdk1p3-cycB) 3)
	(= (need-for-association cycB cdk1p3 cdk1p3-cycB) 1)
	(= (prod-by-association cdk1p3 cycB cdk1p3-cycB) 3)
	(catalyzed-association-reaction cdk1p3-cycB Myt1 cdk1p1p3-cycB)
	(= (need-for-catalyzed-association cdk1p3-cycB Myt1 cdk1p1p3-cycB) 4)
	(= (need-for-catalyzed-association Myt1 cdk1p3-cycB cdk1p1p3-cycB) 3)
	(= (prod-by-catalyzed-association cdk1p3-cycB Myt1 cdk1p1p3-cycB) 1)
	(catalyzed-association-reaction cdk1p3-cycB Wee1 cdk1p2p3-cycB)
	(= (need-for-catalyzed-association cdk1p3-cycB Wee1 cdk1p2p3-cycB) 2)
	(= (need-for-catalyzed-association Wee1 cdk1p3-cycB cdk1p2p3-cycB) 2)
	(= (prod-by-catalyzed-association cdk1p3-cycB Wee1 cdk1p2p3-cycB) 3)
	(association-reaction cdk1p3 Gadd45 cdk1p3-Gadd45)
	(= (need-for-association cdk1p3 Gadd45 cdk1p3-Gadd45) 3)
	(= (need-for-association Gadd45 cdk1p3 cdk1p3-Gadd45) 2)
	(= (prod-by-association cdk1p3 Gadd45 cdk1p3-Gadd45) 3)
	(catalyzed-association-reaction cdk2 cdk7-cycH cdk2p2)
	(= (need-for-catalyzed-association cdk2 cdk7-cycH cdk2p2) 2)
	(= (need-for-catalyzed-association cdk7-cycH cdk2 cdk2p2) 1)
	(= (prod-by-catalyzed-association cdk2 cdk7-cycH cdk2p2) 1)
	(association-reaction cdk2 cks1 cdk2-cks1)
	(= (need-for-association cdk2 cks1 cdk2-cks1) 2)
	(= (need-for-association cks1 cdk2 cdk2-cks1) 3)
	(= (prod-by-association cdk2 cks1 cdk2-cks1) 2)
	(catalyzed-association-reaction cdk2-cycB Wee1 cdk2p1-cycB)
	(= (need-for-catalyzed-association cdk2-cycB Wee1 cdk2p1-cycB) 2)
	(= (need-for-catalyzed-association Wee1 cdk2-cycB cdk2p1-cycB) 1)
	(= (prod-by-catalyzed-association cdk2-cycB Wee1 cdk2p1-cycB) 3)
	(catalyzed-association-reaction cdk2p1 cdk7-cycH cdk2p1p2)
	(= (need-for-catalyzed-association cdk2p1 cdk7-cycH cdk2p1p2) 4)
	(= (need-for-catalyzed-association cdk7-cycH cdk2p1 cdk2p1p2) 4)
	(= (prod-by-catalyzed-association cdk2p1 cdk7-cycH cdk2p1p2) 2)
	(association-reaction cdk2p1 cks1 cdk2p1-cks1)
	(= (need-for-association cdk2p1 cks1 cdk2p1-cks1) 4)
	(= (need-for-association cks1 cdk2p1 cdk2p1-cks1) 3)
	(= (prod-by-association cdk2p1 cks1 cdk2p1-cks1) 4)
	(association-reaction cdk2p1p2 cks1 cdk2p1p2-cks1)
	(= (need-for-association cdk2p1p2 cks1 cdk2p1p2-cks1) 3)
	(= (need-for-association cks1 cdk2p1p2 cdk2p1p2-cks1) 3)
	(= (prod-by-association cdk2p1p2 cks1 cdk2p1p2-cks1) 1)
	(association-reaction cdk2p2 cks1 cdk2p2-cks1)
	(= (need-for-association cdk2p2 cks1 cdk2p2-cks1) 4)
	(= (need-for-association cks1 cdk2p2 cdk2p2-cks1) 1)
	(= (prod-by-association cdk2p2 cks1 cdk2p2-cks1) 1)
	(catalyzed-association-reaction cdk2p2-cycB Wee1 cdk2p1p2-cycB)
	(= (need-for-catalyzed-association cdk2p2-cycB Wee1 cdk2p1p2-cycB) 2)
	(= (need-for-catalyzed-association Wee1 cdk2p2-cycB cdk2p1p2-cycB) 1)
	(= (prod-by-catalyzed-association cdk2p2-cycB Wee1 cdk2p1p2-cycB) 3)
	(catalyzed-association-reaction cdk46p1 cdk7-cycH cdk46p1p2)
	(= (need-for-catalyzed-association cdk46p1 cdk7-cycH cdk46p1p2) 2)
	(= (need-for-catalyzed-association cdk7-cycH cdk46p1 cdk46p1p2) 2)
	(= (prod-by-catalyzed-association cdk46p1 cdk7-cycH cdk46p1p2) 4)
	(catalyzed-association-reaction cdk7 cdk7-cycH cdk7p1)
	(= (need-for-catalyzed-association cdk7 cdk7-cycH cdk7p1) 4)
	(= (need-for-catalyzed-association cdk7-cycH cdk7 cdk7p1) 1)
	(= (prod-by-catalyzed-association cdk7 cdk7-cycH cdk7p1) 1)
	(association-reaction cdk7 cycH cdk7-cycH)
	(= (need-for-association cdk7 cycH cdk7-cycH) 3)
	(= (need-for-association cycH cdk7 cdk7-cycH) 2)
	(= (prod-by-association cdk7 cycH cdk7-cycH) 2)
	(catalyzed-association-reaction cdk7-cycH cdk7-cycH cdk7p1-cycH)
	(= (need-for-catalyzed-association cdk7-cycH cdk7-cycH cdk7p1-cycH) 3)
	(= (need-for-catalyzed-association cdk7-cycH cdk7-cycH cdk7p1-cycH) 3)
	(= (prod-by-catalyzed-association cdk7-cycH cdk7-cycH cdk7p1-cycH) 4)
	(association-reaction cdk7p1 cycH cdk7p1-cycH)
	(= (need-for-association cdk7p1 cycH cdk7p1-cycH) 4)
	(= (need-for-association cycH cdk7p1 cdk7p1-cycH) 4)
	(= (prod-by-association cdk7p1 cycH cdk7p1-cycH) 1)
	(association-reaction CEBP pRb CEBP-pRb)
	(= (need-for-association CEBP pRb CEBP-pRb) 3)
	(= (need-for-association pRb CEBP CEBP-pRb) 4)
	(= (prod-by-association CEBP pRb CEBP-pRb) 4)
	(association-reaction CEBP pRbp1 CEBP-pRbp1)
	(= (need-for-association CEBP pRbp1 CEBP-pRbp1) 4)
	(= (need-for-association pRbp1 CEBP CEBP-pRbp1) 3)
	(= (prod-by-association CEBP pRbp1 CEBP-pRbp1) 2)
	(association-reaction CEBP pRbp1p2 CEBP-pRbp1p2)
	(= (need-for-association CEBP pRbp1p2 CEBP-pRbp1p2) 4)
	(= (need-for-association pRbp1p2 CEBP CEBP-pRbp1p2) 2)
	(= (prod-by-association CEBP pRbp1p2 CEBP-pRbp1p2) 4)
	(association-reaction CEBP pRbp2 CEBP-pRbp2)
	(= (need-for-association CEBP pRbp2 CEBP-pRbp2) 4)
	(= (need-for-association pRbp2 CEBP CEBP-pRbp2) 1)
	(= (prod-by-association CEBP pRbp2 CEBP-pRbp2) 1)
	(catalyzed-association-reaction cycB APCp1 APCp1)
	(= (need-for-catalyzed-association cycB APCp1 APCp1) 1)
	(= (need-for-catalyzed-association APCp1 cycB APCp1) 2)
	(= (prod-by-catalyzed-association cycB APCp1 APCp1) 1)
	(association-reaction E2F1 DP12 E2F1-DP12)
	(= (need-for-association E2F1 DP12 E2F1-DP12) 3)
	(= (need-for-association DP12 E2F1 E2F1-DP12) 4)
	(= (prod-by-association E2F1 DP12 E2F1-DP12) 2)
	(association-reaction E2F2 DP12 E2F2-DP12)
	(= (need-for-association E2F2 DP12 E2F2-DP12) 3)
	(= (need-for-association DP12 E2F2 E2F2-DP12) 3)
	(= (prod-by-association E2F2 DP12 E2F2-DP12) 2)
	(association-reaction E2F3 DP12 E2F3-DP12)
	(= (need-for-association E2F3 DP12 E2F3-DP12) 3)
	(= (need-for-association DP12 E2F3 E2F3-DP12) 1)
	(= (prod-by-association E2F3 DP12 E2F3-DP12) 4)
	(association-reaction E2F4 DP12 E2F4-DP12)
	(= (need-for-association E2F4 DP12 E2F4-DP12) 4)
	(= (need-for-association DP12 E2F4 E2F4-DP12) 4)
	(= (prod-by-association E2F4 DP12 E2F4-DP12) 2)
	(association-reaction E2F5 DP12 E2F5-DP12)
	(= (need-for-association E2F5 DP12 E2F5-DP12) 4)
	(= (need-for-association DP12 E2F5 E2F5-DP12) 3)
	(= (prod-by-association E2F5 DP12 E2F5-DP12) 2)
	(association-reaction E2F6 DP12 E2F6-DP12)
	(= (need-for-association E2F6 DP12 E2F6-DP12) 4)
	(= (need-for-association DP12 E2F6 E2F6-DP12) 1)
	(= (prod-by-association E2F6 DP12 E2F6-DP12) 1)
	(association-reaction HBP1 p130 HBP1-p130)
	(= (need-for-association HBP1 p130 HBP1-p130) 3)
	(= (need-for-association p130 HBP1 HBP1-p130) 1)
	(= (prod-by-association HBP1 p130 HBP1-p130) 3)
	(association-reaction HDAC1 p130-E2F4-DP12 HDAC1-p130-E2F4-DP12)
	(= (need-for-association HDAC1 p130-E2F4-DP12 HDAC1-p130-E2F4-DP12) 1)
	(= (need-for-association p130-E2F4-DP12 HDAC1 HDAC1-p130-E2F4-DP12) 4)
	(= (prod-by-association HDAC1 p130-E2F4-DP12 HDAC1-p130-E2F4-DP12) 4)
	(association-reaction HDAC1 p130-E2F5-DP12 HDAC1-p130-E2F5-DP12)
	(= (need-for-association HDAC1 p130-E2F5-DP12 HDAC1-p130-E2F5-DP12) 4)
	(= (need-for-association p130-E2F5-DP12 HDAC1 HDAC1-p130-E2F5-DP12) 3)
	(= (prod-by-association HDAC1 p130-E2F5-DP12 HDAC1-p130-E2F5-DP12) 4)
	(association-reaction HDAC1 pRb-E2F13-DP12 HDAC1-pRb-E2F13-DP12)
	(= (need-for-association HDAC1 pRb-E2F13-DP12 HDAC1-pRb-E2F13-DP12) 4)
	(= (need-for-association pRb-E2F13-DP12 HDAC1 HDAC1-pRb-E2F13-DP12) 3)
	(= (prod-by-association HDAC1 pRb-E2F13-DP12 HDAC1-pRb-E2F13-DP12) 2)
	(association-reaction HDAC1 pRb-E2F13-DP12p1 HDAC1-pRb-E2F13-DP12p1)
	(= (need-for-association HDAC1 pRb-E2F13-DP12p1 HDAC1-pRb-E2F13-DP12p1) 4)
	(= (need-for-association pRb-E2F13-DP12p1 HDAC1 HDAC1-pRb-E2F13-DP12p1) 2)
	(= (prod-by-association HDAC1 pRb-E2F13-DP12p1 HDAC1-pRb-E2F13-DP12p1) 1)
	(association-reaction HDAC1 pRb-E2F13p1-DP12 HDAC1-pRb-E2F13p1-DP12)
	(= (need-for-association HDAC1 pRb-E2F13p1-DP12 HDAC1-pRb-E2F13p1-DP12) 2)
	(= (need-for-association pRb-E2F13p1-DP12 HDAC1 HDAC1-pRb-E2F13p1-DP12) 4)
	(= (prod-by-association HDAC1 pRb-E2F13p1-DP12 HDAC1-pRb-E2F13p1-DP12) 3)
	(association-reaction HDAC1 pRb-E2F13p1-DP12p1 HDAC1-pRb-E2F13p1-DP12p1)
	(= (need-for-association HDAC1 pRb-E2F13p1-DP12p1 HDAC1-pRb-E2F13p1-DP12p1) 3)
	(= (need-for-association pRb-E2F13p1-DP12p1 HDAC1 HDAC1-pRb-E2F13p1-DP12p1) 2)
	(= (prod-by-association HDAC1 pRb-E2F13p1-DP12p1 HDAC1-pRb-E2F13p1-DP12p1) 4)
	(association-reaction HDAC1 pRb-E2F4-DP12 HDAC1-pRb-E2F4-DP12)
	(= (need-for-association HDAC1 pRb-E2F4-DP12 HDAC1-pRb-E2F4-DP12) 2)
	(= (need-for-association pRb-E2F4-DP12 HDAC1 HDAC1-pRb-E2F4-DP12) 2)
	(= (prod-by-association HDAC1 pRb-E2F4-DP12 HDAC1-pRb-E2F4-DP12) 3)
	(association-reaction Jun c-Fos Jun-c-Fos)
	(= (need-for-association Jun c-Fos Jun-c-Fos) 4)
	(= (need-for-association c-Fos Jun Jun-c-Fos) 1)
	(= (prod-by-association Jun c-Fos Jun-c-Fos) 1)
	(association-reaction m1433 cdc25Cp1p2 m1433-cdc25Cp1p2)
	(= (need-for-association m1433 cdc25Cp1p2 m1433-cdc25Cp1p2) 1)
	(= (need-for-association cdc25Cp1p2 m1433 m1433-cdc25Cp1p2) 4)
	(= (prod-by-association m1433 cdc25Cp1p2 m1433-cdc25Cp1p2) 2)
	(association-reaction m1433 cdc25Cp2 m1433-cdc25Cp2)
	(= (need-for-association m1433 cdc25Cp2 m1433-cdc25Cp2) 1)
	(= (need-for-association cdc25Cp2 m1433 m1433-cdc25Cp2) 2)
	(= (prod-by-association m1433 cdc25Cp2 m1433-cdc25Cp2) 2)
	(association-reaction Mdm2 E2F13-DP12 Mdm2-E2F13-DP12)
	(= (need-for-association Mdm2 E2F13-DP12 Mdm2-E2F13-DP12) 3)
	(= (need-for-association E2F13-DP12 Mdm2 Mdm2-E2F13-DP12) 2)
	(= (prod-by-association Mdm2 E2F13-DP12 Mdm2-E2F13-DP12) 1)
	(association-reaction Mdm2 E2F13-DP12p1 Mdm2-E2F13-DP12p1)
	(= (need-for-association Mdm2 E2F13-DP12p1 Mdm2-E2F13-DP12p1) 3)
	(= (need-for-association E2F13-DP12p1 Mdm2 Mdm2-E2F13-DP12p1) 2)
	(= (prod-by-association Mdm2 E2F13-DP12p1 Mdm2-E2F13-DP12p1) 3)
	(association-reaction Mdm2 E2F13p1-DP12 Mdm2-E2F13p1-DP12)
	(= (need-for-association Mdm2 E2F13p1-DP12 Mdm2-E2F13p1-DP12) 2)
	(= (need-for-association E2F13p1-DP12 Mdm2 Mdm2-E2F13p1-DP12) 1)
	(= (prod-by-association Mdm2 E2F13p1-DP12 Mdm2-E2F13p1-DP12) 2)
	(association-reaction Mdm2 E2F13p1-DP12p1 Mdm2-E2F13p1-DP12p1)
	(= (need-for-association Mdm2 E2F13p1-DP12p1 Mdm2-E2F13p1-DP12p1) 3)
	(= (need-for-association E2F13p1-DP12p1 Mdm2 Mdm2-E2F13p1-DP12p1) 1)
	(= (prod-by-association Mdm2 E2F13p1-DP12p1 Mdm2-E2F13p1-DP12p1) 3)
	(association-reaction Mdm2 pRb Mdm2-pRb)
	(= (need-for-association Mdm2 pRb Mdm2-pRb) 3)
	(= (need-for-association pRb Mdm2 Mdm2-pRb) 2)
	(= (prod-by-association Mdm2 pRb Mdm2-pRb) 2)
	(association-reaction Mdm2 pRbp1 Mdm2-pRbp1)
	(= (need-for-association Mdm2 pRbp1 Mdm2-pRbp1) 2)
	(= (need-for-association pRbp1 Mdm2 Mdm2-pRbp1) 4)
	(= (prod-by-association Mdm2 pRbp1 Mdm2-pRbp1) 3)
	(association-reaction Mdm2 pRbp1p2 Mdm2-pRbp1p2)
	(= (need-for-association Mdm2 pRbp1p2 Mdm2-pRbp1p2) 1)
	(= (need-for-association pRbp1p2 Mdm2 Mdm2-pRbp1p2) 2)
	(= (prod-by-association Mdm2 pRbp1p2 Mdm2-pRbp1p2) 4)
	(association-reaction Mdm2 pRbp2 Mdm2-pRbp2)
	(= (need-for-association Mdm2 pRbp2 Mdm2-pRbp2) 3)
	(= (need-for-association pRbp2 Mdm2 Mdm2-pRbp2) 1)
	(= (prod-by-association Mdm2 pRbp2 Mdm2-pRbp2) 4)
	(association-reaction p130 E2F4-DP12 p130-E2F4-DP12)
	(= (need-for-association p130 E2F4-DP12 p130-E2F4-DP12) 3)
	(= (need-for-association E2F4-DP12 p130 p130-E2F4-DP12) 1)
	(= (prod-by-association p130 E2F4-DP12 p130-E2F4-DP12) 3)
	(association-reaction p130 E2F5-DP12 p130-E2F5-DP12)
	(= (need-for-association p130 E2F5-DP12 p130-E2F5-DP12) 4)
	(= (need-for-association E2F5-DP12 p130 p130-E2F5-DP12) 1)
	(= (prod-by-association p130 E2F5-DP12 p130-E2F5-DP12) 1)
	(association-reaction p16 cdk46p1 p16-cdk46p1)
	(= (need-for-association p16 cdk46p1 p16-cdk46p1) 1)
	(= (need-for-association cdk46p1 p16 p16-cdk46p1) 3)
	(= (prod-by-association p16 cdk46p1 p16-cdk46p1) 2)
	(association-reaction p16 cdk46p1p2 p16-cdk46p1p2)
	(= (need-for-association p16 cdk46p1p2 p16-cdk46p1p2) 1)
	(= (need-for-association cdk46p1p2 p16 p16-cdk46p1p2) 1)
	(= (prod-by-association p16 cdk46p1p2 p16-cdk46p1p2) 3)
	(association-reaction p16 cdk7 p16-cdk7)
	(= (need-for-association p16 cdk7 p16-cdk7) 4)
	(= (need-for-association cdk7 p16 p16-cdk7) 3)
	(= (prod-by-association p16 cdk7 p16-cdk7) 4)
	(association-reaction p16 cdk7p1 p16-cdk7p1)
	(= (need-for-association p16 cdk7p1 p16-cdk7p1) 1)
	(= (need-for-association cdk7p1 p16 p16-cdk7p1) 1)
	(= (prod-by-association p16 cdk7p1 p16-cdk7p1) 4)
	(association-reaction p21 Gadd45 p21-Gadd45)
	(= (need-for-association p21 Gadd45 p21-Gadd45) 3)
	(= (need-for-association Gadd45 p21 p21-Gadd45) 4)
	(= (prod-by-association p21 Gadd45 p21-Gadd45) 1)
	(synthesis-reaction p53 c-Fos) 
	(= (need-for-synthesis p53 c-Fos) 4)
	(= (prod-by-synthesis p53 c-Fos) 1)
	(association-reaction p53 DP12 p53-DP12)
	(= (need-for-association p53 DP12 p53-DP12) 4)
	(= (need-for-association DP12 p53 p53-DP12) 2)
	(= (prod-by-association p53 DP12 p53-DP12) 1)
	(synthesis-reaction p53 Gadd45) 
	(= (need-for-synthesis p53 Gadd45) 1)
	(= (prod-by-synthesis p53 Gadd45) 2)
	(synthesis-reaction p53 Mdm2) 
	(= (need-for-synthesis p53 Mdm2) 3)
	(= (prod-by-synthesis p53 Mdm2) 1)
	(synthesis-reaction p53 p21) 
	(= (need-for-synthesis p53 p21) 1)
	(= (prod-by-synthesis p53 p21) 1)
	(association-reaction PCNA Gadd45 PCNA-Gadd45)
	(= (need-for-association PCNA Gadd45 PCNA-Gadd45) 1)
	(= (need-for-association Gadd45 PCNA PCNA-Gadd45) 4)
	(= (prod-by-association PCNA Gadd45 PCNA-Gadd45) 1)
	(association-reaction PCNA p21 PCNA-p21)
	(= (need-for-association PCNA p21 PCNA-p21) 1)
	(= (need-for-association p21 PCNA PCNA-p21) 4)
	(= (prod-by-association PCNA p21 PCNA-p21) 1)
	(synthesis-reaction pRb-AP2-gE-c Ecadherin) 
	(= (need-for-synthesis pRb-AP2-gE-c Ecadherin) 4)
	(= (prod-by-synthesis pRb-AP2-gE-c Ecadherin) 1)
	(association-reaction pRb-AP2 gE-c pRb-AP2-gE-c)
	(= (need-for-association pRb-AP2 gE-c pRb-AP2-gE-c) 2)
	(= (need-for-association gE-c pRb-AP2 pRb-AP2-gE-c) 4)
	(= (prod-by-association pRb-AP2 gE-c pRb-AP2-gE-c) 4)
	(association-reaction pRb AP2 pRb-AP2)
	(= (need-for-association pRb AP2 pRb-AP2) 1)
	(= (need-for-association AP2 pRb pRb-AP2) 2)
	(= (prod-by-association pRb AP2 pRb-AP2) 3)
	(catalyzed-association-reaction pRb cdk46p3-cycDp1 pRbp1)
	(= (need-for-catalyzed-association pRb cdk46p3-cycDp1 pRbp1) 1)
	(= (need-for-catalyzed-association cdk46p3-cycDp1 pRb pRbp1) 3)
	(= (prod-by-catalyzed-association pRb cdk46p3-cycDp1 pRbp1) 2)
	(catalyzed-association-reaction pRb cdk46p3-cycD pRbp1)
	(= (need-for-catalyzed-association pRb cdk46p3-cycD pRbp1) 3)
	(= (need-for-catalyzed-association cdk46p3-cycD pRb pRbp1) 2)
	(= (prod-by-catalyzed-association pRb cdk46p3-cycD pRbp1) 2)
	(association-reaction pRb E2F13-DP12p1 pRb-E2F13-DP12p1)
	(= (need-for-association pRb E2F13-DP12p1 pRb-E2F13-DP12p1) 2)
	(= (need-for-association E2F13-DP12p1 pRb pRb-E2F13-DP12p1) 2)
	(= (prod-by-association pRb E2F13-DP12p1 pRb-E2F13-DP12p1) 1)
	(association-reaction pRb E2F13-DP12 pRb-E2F13-DP12)
	(= (need-for-association pRb E2F13-DP12 pRb-E2F13-DP12) 3)
	(= (need-for-association E2F13-DP12 pRb pRb-E2F13-DP12) 2)
	(= (prod-by-association pRb E2F13-DP12 pRb-E2F13-DP12) 2)
	(association-reaction pRb E2F13p1-DP12p1 pRb-E2F13p1-DP12p1)
	(= (need-for-association pRb E2F13p1-DP12p1 pRb-E2F13p1-DP12p1) 4)
	(= (need-for-association E2F13p1-DP12p1 pRb pRb-E2F13p1-DP12p1) 4)
	(= (prod-by-association pRb E2F13p1-DP12p1 pRb-E2F13p1-DP12p1) 2)
	(association-reaction pRb E2F13p1-DP12 pRb-E2F13p1-DP12)
	(= (need-for-association pRb E2F13p1-DP12 pRb-E2F13p1-DP12) 1)
	(= (need-for-association E2F13p1-DP12 pRb pRb-E2F13p1-DP12) 4)
	(= (prod-by-association pRb E2F13p1-DP12 pRb-E2F13p1-DP12) 3)
	(association-reaction pRb E2F4-DP12 pRb-E2F4-DP12)
	(= (need-for-association pRb E2F4-DP12 pRb-E2F4-DP12) 4)
	(= (need-for-association E2F4-DP12 pRb pRb-E2F4-DP12) 4)
	(= (prod-by-association pRb E2F4-DP12 pRb-E2F4-DP12) 3)
	(association-reaction pRb-Jun c-Fos pRb-Jun-c-Fos)
	(= (need-for-association pRb-Jun c-Fos pRb-Jun-c-Fos) 3)
	(= (need-for-association c-Fos pRb-Jun pRb-Jun-c-Fos) 1)
	(= (prod-by-association pRb-Jun c-Fos pRb-Jun-c-Fos) 2)
	(association-reaction pRb Jun pRb-Jun)
	(= (need-for-association pRb Jun pRb-Jun) 3)
	(= (need-for-association Jun pRb pRb-Jun) 2)
	(= (prod-by-association pRb Jun pRb-Jun) 2)
	(synthesis-reaction pRbp1-AP2-gE-c Ecadherin) 
	(= (need-for-synthesis pRbp1-AP2-gE-c Ecadherin) 2)
	(= (prod-by-synthesis pRbp1-AP2-gE-c Ecadherin) 2)
	(association-reaction pRbp1-AP2 gE-c pRbp1-AP2-gE-c)
	(= (need-for-association pRbp1-AP2 gE-c pRbp1-AP2-gE-c) 3)
	(= (need-for-association gE-c pRbp1-AP2 pRbp1-AP2-gE-c) 4)
	(= (prod-by-association pRbp1-AP2 gE-c pRbp1-AP2-gE-c) 2)
	(association-reaction pRbp1 AP2 pRbp1-AP2)
	(= (need-for-association pRbp1 AP2 pRbp1-AP2) 1)
	(= (need-for-association AP2 pRbp1 pRbp1-AP2) 1)
	(= (prod-by-association pRbp1 AP2 pRbp1-AP2) 4)
	(association-reaction pRbp1 E2F13-DP12p1 pRbp1-E2F13-DP12p1)
	(= (need-for-association pRbp1 E2F13-DP12p1 pRbp1-E2F13-DP12p1) 2)
	(= (need-for-association E2F13-DP12p1 pRbp1 pRbp1-E2F13-DP12p1) 2)
	(= (prod-by-association pRbp1 E2F13-DP12p1 pRbp1-E2F13-DP12p1) 1)
	(association-reaction pRbp1 E2F13-DP12 pRbp1-E2F13-DP12)
	(= (need-for-association pRbp1 E2F13-DP12 pRbp1-E2F13-DP12) 3)
	(= (need-for-association E2F13-DP12 pRbp1 pRbp1-E2F13-DP12) 3)
	(= (prod-by-association pRbp1 E2F13-DP12 pRbp1-E2F13-DP12) 3)
	(association-reaction pRbp1 E2F13p1-DP12p1 pRbp1-E2F13p1-DP12p1)
	(= (need-for-association pRbp1 E2F13p1-DP12p1 pRbp1-E2F13p1-DP12p1) 4)
	(= (need-for-association E2F13p1-DP12p1 pRbp1 pRbp1-E2F13p1-DP12p1) 4)
	(= (prod-by-association pRbp1 E2F13p1-DP12p1 pRbp1-E2F13p1-DP12p1) 3)
	(association-reaction pRbp1 E2F13p1-DP12 pRbp1-E2F13p1-DP12)
	(= (need-for-association pRbp1 E2F13p1-DP12 pRbp1-E2F13p1-DP12) 3)
	(= (need-for-association E2F13p1-DP12 pRbp1 pRbp1-E2F13p1-DP12) 1)
	(= (prod-by-association pRbp1 E2F13p1-DP12 pRbp1-E2F13p1-DP12) 3)
	(association-reaction pRbp1 E2F4-DP12 pRbp1-E2F4-DP12)
	(= (need-for-association pRbp1 E2F4-DP12 pRbp1-E2F4-DP12) 3)
	(= (need-for-association E2F4-DP12 pRbp1 pRbp1-E2F4-DP12) 3)
	(= (prod-by-association pRbp1 E2F4-DP12 pRbp1-E2F4-DP12) 2)
	(association-reaction pRbp1-Jun c-Fos pRbp1-Jun-c-Fos)
	(= (need-for-association pRbp1-Jun c-Fos pRbp1-Jun-c-Fos) 2)
	(= (need-for-association c-Fos pRbp1-Jun pRbp1-Jun-c-Fos) 2)
	(= (prod-by-association pRbp1-Jun c-Fos pRbp1-Jun-c-Fos) 4)
	(association-reaction pRbp1 Jun pRbp1-Jun)
	(= (need-for-association pRbp1 Jun pRbp1-Jun) 2)
	(= (need-for-association Jun pRbp1 pRbp1-Jun) 3)
	(= (prod-by-association pRbp1 Jun pRbp1-Jun) 2)
	(synthesis-reaction pRbp1p2-AP2-gE-c Ecadherin) 
	(= (need-for-synthesis pRbp1p2-AP2-gE-c Ecadherin) 3)
	(= (prod-by-synthesis pRbp1p2-AP2-gE-c Ecadherin) 4)
	(association-reaction pRbp1p2-AP2 gE-c pRbp1p2-AP2-gE-c)
	(= (need-for-association pRbp1p2-AP2 gE-c pRbp1p2-AP2-gE-c) 4)
	(= (need-for-association gE-c pRbp1p2-AP2 pRbp1p2-AP2-gE-c) 4)
	(= (prod-by-association pRbp1p2-AP2 gE-c pRbp1p2-AP2-gE-c) 3)
	(association-reaction pRbp1p2 AP2 pRbp1p2-AP2)
	(= (need-for-association pRbp1p2 AP2 pRbp1p2-AP2) 3)
	(= (need-for-association AP2 pRbp1p2 pRbp1p2-AP2) 1)
	(= (prod-by-association pRbp1p2 AP2 pRbp1p2-AP2) 3)
	(association-reaction pRbp1p2-Jun c-Fos pRbp1p2-Jun-c-Fos)
	(= (need-for-association pRbp1p2-Jun c-Fos pRbp1p2-Jun-c-Fos) 4)
	(= (need-for-association c-Fos pRbp1p2-Jun pRbp1p2-Jun-c-Fos) 4)
	(= (prod-by-association pRbp1p2-Jun c-Fos pRbp1p2-Jun-c-Fos) 1)
	(association-reaction pRbp1p2 Jun pRbp1p2-Jun)
	(= (need-for-association pRbp1p2 Jun pRbp1p2-Jun) 1)
	(= (need-for-association Jun pRbp1p2 pRbp1p2-Jun) 4)
	(= (prod-by-association pRbp1p2 Jun pRbp1p2-Jun) 3)
	(synthesis-reaction pRbp2-AP2-gE-c Ecadherin) 
	(= (need-for-synthesis pRbp2-AP2-gE-c Ecadherin) 3)
	(= (prod-by-synthesis pRbp2-AP2-gE-c Ecadherin) 3)
	(association-reaction pRbp2-AP2 gE-c pRbp2-AP2-gE-c)
	(= (need-for-association pRbp2-AP2 gE-c pRbp2-AP2-gE-c) 3)
	(= (need-for-association gE-c pRbp2-AP2 pRbp2-AP2-gE-c) 2)
	(= (prod-by-association pRbp2-AP2 gE-c pRbp2-AP2-gE-c) 1)
	(association-reaction pRbp2 AP2 pRbp2-AP2)
	(= (need-for-association pRbp2 AP2 pRbp2-AP2) 1)
	(= (need-for-association AP2 pRbp2 pRbp2-AP2) 3)
	(= (prod-by-association pRbp2 AP2 pRbp2-AP2) 3)
	(catalyzed-association-reaction pRbp2 cdk46p3-cycDp1 pRbp1p2)
	(= (need-for-catalyzed-association pRbp2 cdk46p3-cycDp1 pRbp1p2) 3)
	(= (need-for-catalyzed-association cdk46p3-cycDp1 pRbp2 pRbp1p2) 1)
	(= (prod-by-catalyzed-association pRbp2 cdk46p3-cycDp1 pRbp1p2) 4)
	(catalyzed-association-reaction pRbp2 cdk46p3-cycD pRbp1p2)
	(= (need-for-catalyzed-association pRbp2 cdk46p3-cycD pRbp1p2) 1)
	(= (need-for-catalyzed-association cdk46p3-cycD pRbp2 pRbp1p2) 2)
	(= (prod-by-catalyzed-association pRbp2 cdk46p3-cycD pRbp1p2) 3)
	(association-reaction pRbp2-Jun c-Fos pRbp2-Jun-c-Fos)
	(= (need-for-association pRbp2-Jun c-Fos pRbp2-Jun-c-Fos) 2)
	(= (need-for-association c-Fos pRbp2-Jun pRbp2-Jun-c-Fos) 1)
	(= (prod-by-association pRbp2-Jun c-Fos pRbp2-Jun-c-Fos) 4)
	(association-reaction pRbp2 Jun pRbp2-Jun)
	(= (need-for-association pRbp2 Jun pRbp2-Jun) 1)
	(= (need-for-association Jun pRbp2 pRbp2-Jun) 4)
	(= (prod-by-association pRbp2 Jun pRbp2-Jun) 3)
	(association-reaction Raf1 p130-E2F4-DP12 Raf1-p130-E2F4-DP12)
	(= (need-for-association Raf1 p130-E2F4-DP12 Raf1-p130-E2F4-DP12) 4)
	(= (need-for-association p130-E2F4-DP12 Raf1 Raf1-p130-E2F4-DP12) 2)
	(= (prod-by-association Raf1 p130-E2F4-DP12 Raf1-p130-E2F4-DP12) 2)
	(association-reaction Raf1 p130-E2F4p1-DP12 Raf1-p130-E2F4p1-DP12)
	(= (need-for-association Raf1 p130-E2F4p1-DP12 Raf1-p130-E2F4p1-DP12) 1)
	(= (need-for-association p130-E2F4p1-DP12 Raf1 Raf1-p130-E2F4p1-DP12) 1)
	(= (prod-by-association Raf1 p130-E2F4p1-DP12 Raf1-p130-E2F4p1-DP12) 1)
	(association-reaction Raf1 p130-E2F5-DP12 Raf1-p130-E2F5-DP12)
	(= (need-for-association Raf1 p130-E2F5-DP12 Raf1-p130-E2F5-DP12) 4)
	(= (need-for-association p130-E2F5-DP12 Raf1 Raf1-p130-E2F5-DP12) 1)
	(= (prod-by-association Raf1 p130-E2F5-DP12 Raf1-p130-E2F5-DP12) 1)
	(association-reaction Raf1 p130-E2F5p1-DP12 Raf1-p130-E2F5p1-DP12)
	(= (need-for-association Raf1 p130-E2F5p1-DP12 Raf1-p130-E2F5p1-DP12) 4)
	(= (need-for-association p130-E2F5p1-DP12 Raf1 Raf1-p130-E2F5p1-DP12) 3)
	(= (prod-by-association Raf1 p130-E2F5p1-DP12 Raf1-p130-E2F5p1-DP12) 4)
	(association-reaction Raf1 pRb-E2F13-DP12p1 Raf1-pRb-E2F13-DP12p1)
	(= (need-for-association Raf1 pRb-E2F13-DP12p1 Raf1-pRb-E2F13-DP12p1) 2)
	(= (need-for-association pRb-E2F13-DP12p1 Raf1 Raf1-pRb-E2F13-DP12p1) 1)
	(= (prod-by-association Raf1 pRb-E2F13-DP12p1 Raf1-pRb-E2F13-DP12p1) 1)
	(association-reaction Raf1 pRb-E2F13-DP12 Raf1-pRb-E2F13-DP12)
	(= (need-for-association Raf1 pRb-E2F13-DP12 Raf1-pRb-E2F13-DP12) 2)
	(= (need-for-association pRb-E2F13-DP12 Raf1 Raf1-pRb-E2F13-DP12) 2)
	(= (prod-by-association Raf1 pRb-E2F13-DP12 Raf1-pRb-E2F13-DP12) 3)
	(association-reaction Raf1 pRb-E2F13p1-DP12p1 Raf1-pRb-E2F13p1-DP12p1)
	(= (need-for-association Raf1 pRb-E2F13p1-DP12p1 Raf1-pRb-E2F13p1-DP12p1) 4)
	(= (need-for-association pRb-E2F13p1-DP12p1 Raf1 Raf1-pRb-E2F13p1-DP12p1) 4)
	(= (prod-by-association Raf1 pRb-E2F13p1-DP12p1 Raf1-pRb-E2F13p1-DP12p1) 4)
	(association-reaction Raf1 pRb-E2F13p1-DP12 Raf1-pRb-E2F13p1-DP12)
	(= (need-for-association Raf1 pRb-E2F13p1-DP12 Raf1-pRb-E2F13p1-DP12) 3)
	(= (need-for-association pRb-E2F13p1-DP12 Raf1 Raf1-pRb-E2F13p1-DP12) 4)
	(= (prod-by-association Raf1 pRb-E2F13p1-DP12 Raf1-pRb-E2F13p1-DP12) 1)
	(association-reaction Raf1 pRb-E2F4-DP12 Raf1-pRb-E2F4-DP12)
	(= (need-for-association Raf1 pRb-E2F4-DP12 Raf1-pRb-E2F4-DP12) 1)
	(= (need-for-association pRb-E2F4-DP12 Raf1 Raf1-pRb-E2F4-DP12) 2)
	(= (prod-by-association Raf1 pRb-E2F4-DP12 Raf1-pRb-E2F4-DP12) 1)
	(association-reaction Raf1 pRbp1-E2F13-DP12p1 Raf1-pRbp1-E2F13-DP12p1)
	(= (need-for-association Raf1 pRbp1-E2F13-DP12p1 Raf1-pRbp1-E2F13-DP12p1) 4)
	(= (need-for-association pRbp1-E2F13-DP12p1 Raf1 Raf1-pRbp1-E2F13-DP12p1) 2)
	(= (prod-by-association Raf1 pRbp1-E2F13-DP12p1 Raf1-pRbp1-E2F13-DP12p1) 1)
	(association-reaction Raf1 pRbp1-E2F13-DP12 Raf1-pRbp1-E2F13-DP12)
	(= (need-for-association Raf1 pRbp1-E2F13-DP12 Raf1-pRbp1-E2F13-DP12) 3)
	(= (need-for-association pRbp1-E2F13-DP12 Raf1 Raf1-pRbp1-E2F13-DP12) 1)
	(= (prod-by-association Raf1 pRbp1-E2F13-DP12 Raf1-pRbp1-E2F13-DP12) 2)
	(association-reaction Raf1 pRbp1-E2F13p1-DP12p1 Raf1-pRbp1-E2F13p1-DP12p1)
	(= (need-for-association Raf1 pRbp1-E2F13p1-DP12p1 Raf1-pRbp1-E2F13p1-DP12p1) 4)
	(= (need-for-association pRbp1-E2F13p1-DP12p1 Raf1 Raf1-pRbp1-E2F13p1-DP12p1) 1)
	(= (prod-by-association Raf1 pRbp1-E2F13p1-DP12p1 Raf1-pRbp1-E2F13p1-DP12p1) 2)
	(association-reaction Raf1 pRbp1-E2F13p1-DP12 Raf1-pRbp1-E2F13p1-DP12)
	(= (need-for-association Raf1 pRbp1-E2F13p1-DP12 Raf1-pRbp1-E2F13p1-DP12) 4)
	(= (need-for-association pRbp1-E2F13p1-DP12 Raf1 Raf1-pRbp1-E2F13p1-DP12) 1)
	(= (prod-by-association Raf1 pRbp1-E2F13p1-DP12 Raf1-pRbp1-E2F13p1-DP12) 2)
	(association-reaction Raf1 pRbp1-E2F4-DP12 Raf1-pRbp1-E2F4-DP12)
	(= (need-for-association Raf1 pRbp1-E2F4-DP12 Raf1-pRbp1-E2F4-DP12) 4)
	(= (need-for-association pRbp1-E2F4-DP12 Raf1 Raf1-pRbp1-E2F4-DP12) 4)
	(= (prod-by-association Raf1 pRbp1-E2F4-DP12 Raf1-pRbp1-E2F4-DP12) 1)
	(association-reaction Raf1 pRbp1-E2F4p1-DP12 Raf1-pRbp1-E2F4p1-DP12)
	(= (need-for-association Raf1 pRbp1-E2F4p1-DP12 Raf1-pRbp1-E2F4p1-DP12) 3)
	(= (need-for-association pRbp1-E2F4p1-DP12 Raf1 Raf1-pRbp1-E2F4p1-DP12) 1)
	(= (prod-by-association Raf1 pRbp1-E2F4p1-DP12 Raf1-pRbp1-E2F4p1-DP12) 1)
	(catalyzed-association-reaction SL1 cdk1p3-cycB SL1p1)
	(= (need-for-catalyzed-association SL1 cdk1p3-cycB SL1p1) 4)
	(= (need-for-catalyzed-association cdk1p3-cycB SL1 SL1p1) 2)
	(= (prod-by-catalyzed-association SL1 cdk1p3-cycB SL1p1) 2)
	(catalyzed-association-reaction Wee1 cdk1p3-cycB Wee1p1)
	(= (need-for-catalyzed-association Wee1 cdk1p3-cycB Wee1p1) 2)
	(= (need-for-catalyzed-association cdk1p3-cycB Wee1 Wee1p1) 1)
	(= (prod-by-catalyzed-association Wee1 cdk1p3-cycB Wee1p1) 2)
	(= (num-subs) 0)
	(= (duration-association-reaction AP2 gE-c AP2-gE-c) 1.1)
	(= (duration-synthesis-reaction AP2-gE-c Ecadherin) 4.5)
	(= (duration-catalyzed-association-reaction APC Plk1 APCp1) 2.1)
	(= (duration-association-reaction c-Abl pRb c-Abl-pRb) 0.8)
	(= (duration-association-reaction c-Abl pRbp1 c-Abl-pRbp1) 1.1)
	(= (duration-association-reaction c-Abl pRbp1p2 c-Abl-pRbp1p2) 0.9)
	(= (duration-association-reaction c-Abl pRbp2 c-Abl-pRbp2) 1.1)
	(= (duration-catalyzed-association-reaction cdc25C cdk1p3-cycB cdc25Cp1) 2.0)
	(= (duration-catalyzed-association-reaction cdc25C C-TAK1 cdc25Cp2) 2.2)
	(= (duration-catalyzed-association-reaction cdc25Cp1 C-TAK1 cdc25Cp1p2) 1.6)
	(= (duration-catalyzed-association-reaction cdc25Cp2 cdk1p3-cycB cdc25Cp1p2) 2.0)
	(= (duration-catalyzed-association-reaction cdc25Cp2 Plk1 cdc25Cp1p2) 1.8)
	(= (duration-catalyzed-association-reaction cdc25C Plk1 cdc25Cp1) 1.7)
	(= (duration-catalyzed-association-reaction cdk1 cdk7-cycH cdk1p3) 2.1)
	(= (duration-association-reaction cdk1 cks1 cdk1-cks1) 0.9)
	(= (duration-association-reaction cdk1 Gadd45 cdk1-Gadd45) 1.1)
	(= (duration-catalyzed-association-reaction cdk1p1 cdc25Cp1 cdk1) 1.7)
	(= (duration-catalyzed-association-reaction cdk1p1 cdc25Cp1p2 cdk1) 1.9)
	(= (duration-catalyzed-association-reaction cdk1p1 cdk7-cycH cdk1p1p3) 2.2)
	(= (duration-association-reaction cdk1p1 cks1 cdk1p1-cks1) 1.1)
	(= (duration-association-reaction cdk1p1 Gadd45 cdk1p1-Gadd45) 0.9)
	(= (duration-catalyzed-association-reaction cdk1p1p2 cdc25Cp1 cdk1p1) 1.6)
	(= (duration-catalyzed-association-reaction cdk1p1p2 cdc25Cp1 cdk1p2) 1.8)
	(= (duration-catalyzed-association-reaction cdk1p1p2 cdc25Cp1p2 cdk1p1) 2.0)
	(= (duration-catalyzed-association-reaction cdk1p1p2 cdc25Cp1p2 cdk1p2) 2.0)
	(= (duration-catalyzed-association-reaction cdk1p1p2 cdk7-cycH cdk1p1p2p3) 2.3)
	(= (duration-association-reaction cdk1p1p2 cks1 cdk1p1p2-cks1) 1.1)
	(= (duration-association-reaction cdk1p1p2 Gadd45 cdk1p1p2-Gadd45) 1.1)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1 cdk1p1p3) 2.2)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1 cdk1p2p3) 2.3)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1p2 cdk1p1p3) 1.9)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3 cdc25Cp1p2 cdk1p2p3) 1.8)
	(= (duration-association-reaction cdk1p1p2p3 cks1 cdk1p1p2p3-cks1) 1.1)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1 cdk1p1p3-cycB) 2.1)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1 cdk1p2p3-cycB) 2.1)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p1p3-cycB) 1.9)
	(= (duration-catalyzed-association-reaction cdk1p1p2p3-cycB cdc25Cp1p2 cdk1p2p3-cycB) 2.3)
	(= (duration-association-reaction cdk1p1p2p3 cycB cdk1p1p2p3-cycB) 0.8)
	(= (duration-association-reaction cdk1p1p2p3 Gadd45 cdk1p1p2p3-Gadd45) 1.1)
	(= (duration-catalyzed-association-reaction cdk1p1p3 cdc25Cp1 cdk1p3) 2.2)
	(= (duration-catalyzed-association-reaction cdk1p1p3 cdc25Cp1p2 cdk1p3) 1.7)
	(= (duration-association-reaction cdk1p1p3 cks1 cdk1p1p3-cks1) 1.1)
	(= (duration-catalyzed-association-reaction cdk1p1p3-cycB cdc25Cp1 cdk1p3-cycB) 2.0)
	(= (duration-catalyzed-association-reaction cdk1p1p3-cycB cdc25Cp1p2 cdk1p3-cycB) 2.1)
	(= (duration-association-reaction cdk1p1p3 cycB cdk1p1p3-cycB) 1.0)
	(= (duration-catalyzed-association-reaction cdk1p1p3-cycB Wee1 cdk1p1p2p3-cycB) 1.9)
	(= (duration-association-reaction cdk1p1p3 Gadd45 cdk1p1p3-Gadd45) 0.8)
	(= (duration-catalyzed-association-reaction cdk1p2 cdc25Cp1 cdk1) 1.8)
	(= (duration-catalyzed-association-reaction cdk1p2 cdc25Cp1p2 cdk1) 2.2)
	(= (duration-catalyzed-association-reaction cdk1p2 cdk7-cycH cdk1p2p3) 2.3)
	(= (duration-association-reaction cdk1p2 cks1 cdk1p2-cks1) 0.8)
	(= (duration-association-reaction cdk1p2 Gadd45 cdk1p2-Gadd45) 1.0)
	(= (duration-catalyzed-association-reaction cdk1p2p3 cdc25Cp1 cdk1p3) 1.6)
	(= (duration-catalyzed-association-reaction cdk1p2p3 cdc25Cp1p2 cdk1p3) 1.8)
	(= (duration-association-reaction cdk1p2p3 cks1 cdk1p2p3-cks1) 1.1)
	(= (duration-catalyzed-association-reaction cdk1p2p3-cycB cdc25Cp1 cdk1p3-cycB) 1.6)
	(= (duration-catalyzed-association-reaction cdk1p2p3-cycB cdc25Cp1p2 cdk1p3-cycB) 2.1)
	(= (duration-association-reaction cdk1p2p3 cycB cdk1p2p3-cycB) 0.8)
	(= (duration-catalyzed-association-reaction cdk1p2p3-cycB Myt1 cdk1p1p2p3-cycB) 2.2)
	(= (duration-association-reaction cdk1p2p3 Gadd45 cdk1p2p3-Gadd45) 0.8)
	(= (duration-association-reaction cdk1p3 cks1 cdk1p3-cks1) 0.8)
	(= (duration-association-reaction cdk1p3 cycB cdk1p3-cycB) 1.1)
	(= (duration-catalyzed-association-reaction cdk1p3-cycB Myt1 cdk1p1p3-cycB) 1.9)
	(= (duration-catalyzed-association-reaction cdk1p3-cycB Wee1 cdk1p2p3-cycB) 1.9)
	(= (duration-association-reaction cdk1p3 Gadd45 cdk1p3-Gadd45) 1.0)
	(= (duration-catalyzed-association-reaction cdk2 cdk7-cycH cdk2p2) 1.7)
	(= (duration-association-reaction cdk2 cks1 cdk2-cks1) 1.1)
	(= (duration-catalyzed-association-reaction cdk2-cycB Wee1 cdk2p1-cycB) 2.2)
	(= (duration-catalyzed-association-reaction cdk2p1 cdk7-cycH cdk2p1p2) 1.7)
	(= (duration-association-reaction cdk2p1 cks1 cdk2p1-cks1) 0.9)
	(= (duration-association-reaction cdk2p1p2 cks1 cdk2p1p2-cks1) 0.9)
	(= (duration-association-reaction cdk2p2 cks1 cdk2p2-cks1) 1.0)
	(= (duration-catalyzed-association-reaction cdk2p2-cycB Wee1 cdk2p1p2-cycB) 1.7)
	(= (duration-catalyzed-association-reaction cdk46p1 cdk7-cycH cdk46p1p2) 2.2)
	(= (duration-catalyzed-association-reaction cdk7 cdk7-cycH cdk7p1) 1.9)
	(= (duration-association-reaction cdk7 cycH cdk7-cycH) 1.1)
	(= (duration-catalyzed-association-reaction cdk7-cycH cdk7-cycH cdk7p1-cycH) 2.1)
	(= (duration-association-reaction cdk7p1 cycH cdk7p1-cycH) 1.0)
	(= (duration-association-reaction CEBP pRb CEBP-pRb) 1.0)
	(= (duration-association-reaction CEBP pRbp1 CEBP-pRbp1) 1.1)
	(= (duration-association-reaction CEBP pRbp1p2 CEBP-pRbp1p2) 1.0)
	(= (duration-association-reaction CEBP pRbp2 CEBP-pRbp2) 1.0)
	(= (duration-catalyzed-association-reaction cycB APCp1 APCp1) 2.1)
	(= (duration-association-reaction E2F1 DP12 E2F1-DP12) 1.0)
	(= (duration-association-reaction E2F2 DP12 E2F2-DP12) 0.9)
	(= (duration-association-reaction E2F3 DP12 E2F3-DP12) 1.1)
	(= (duration-association-reaction E2F4 DP12 E2F4-DP12) 0.8)
	(= (duration-association-reaction E2F5 DP12 E2F5-DP12) 1.0)
	(= (duration-association-reaction E2F6 DP12 E2F6-DP12) 1.1)
	(= (duration-association-reaction HBP1 p130 HBP1-p130) 1.1)
	(= (duration-association-reaction HDAC1 p130-E2F4-DP12 HDAC1-p130-E2F4-DP12) 1.1)
	(= (duration-association-reaction HDAC1 p130-E2F5-DP12 HDAC1-p130-E2F5-DP12) 1.0)
	(= (duration-association-reaction HDAC1 pRb-E2F13-DP12 HDAC1-pRb-E2F13-DP12) 0.9)
	(= (duration-association-reaction HDAC1 pRb-E2F13-DP12p1 HDAC1-pRb-E2F13-DP12p1) 0.8)
	(= (duration-association-reaction HDAC1 pRb-E2F13p1-DP12 HDAC1-pRb-E2F13p1-DP12) 1.1)
	(= (duration-association-reaction HDAC1 pRb-E2F13p1-DP12p1 HDAC1-pRb-E2F13p1-DP12p1) 0.9)
	(= (duration-association-reaction HDAC1 pRb-E2F4-DP12 HDAC1-pRb-E2F4-DP12) 1.0)
	(= (duration-association-reaction Jun c-Fos Jun-c-Fos) 0.9)
	(= (duration-association-reaction m1433 cdc25Cp1p2 m1433-cdc25Cp1p2) 0.8)
	(= (duration-association-reaction m1433 cdc25Cp2 m1433-cdc25Cp2) 0.9)
	(= (duration-association-reaction Mdm2 E2F13-DP12 Mdm2-E2F13-DP12) 0.9)
	(= (duration-association-reaction Mdm2 E2F13-DP12p1 Mdm2-E2F13-DP12p1) 1.1)
	(= (duration-association-reaction Mdm2 E2F13p1-DP12 Mdm2-E2F13p1-DP12) 0.8)
	(= (duration-association-reaction Mdm2 E2F13p1-DP12p1 Mdm2-E2F13p1-DP12p1) 1.0)
	(= (duration-association-reaction Mdm2 pRb Mdm2-pRb) 1.0)
	(= (duration-association-reaction Mdm2 pRbp1 Mdm2-pRbp1) 1.0)
	(= (duration-association-reaction Mdm2 pRbp1p2 Mdm2-pRbp1p2) 1.1)
	(= (duration-association-reaction Mdm2 pRbp2 Mdm2-pRbp2) 1.1)
	(= (duration-association-reaction p130 E2F4-DP12 p130-E2F4-DP12) 0.8)
	(= (duration-association-reaction p130 E2F5-DP12 p130-E2F5-DP12) 0.9)
	(= (duration-association-reaction p16 cdk46p1 p16-cdk46p1) 1.0)
	(= (duration-association-reaction p16 cdk46p1p2 p16-cdk46p1p2) 1.0)
	(= (duration-association-reaction p16 cdk7 p16-cdk7) 1.0)
	(= (duration-association-reaction p16 cdk7p1 p16-cdk7p1) 1.1)
	(= (duration-association-reaction p21 Gadd45 p21-Gadd45) 1.1)
	(= (duration-synthesis-reaction p53 c-Fos) 3.7)
	(= (duration-association-reaction p53 DP12 p53-DP12) 1.0)
	(= (duration-synthesis-reaction p53 Gadd45) 4.4)
	(= (duration-synthesis-reaction p53 Mdm2) 3.3)
	(= (duration-synthesis-reaction p53 p21) 3.4)
	(= (duration-association-reaction PCNA Gadd45 PCNA-Gadd45) 0.9)
	(= (duration-association-reaction PCNA p21 PCNA-p21) 1.1)
	(= (duration-synthesis-reaction pRb-AP2-gE-c Ecadherin) 4.1)
	(= (duration-association-reaction pRb-AP2 gE-c pRb-AP2-gE-c) 0.8)
	(= (duration-association-reaction pRb AP2 pRb-AP2) 1.0)
	(= (duration-catalyzed-association-reaction pRb cdk46p3-cycDp1 pRbp1) 2.0)
	(= (duration-catalyzed-association-reaction pRb cdk46p3-cycD pRbp1) 1.8)
	(= (duration-association-reaction pRb E2F13-DP12p1 pRb-E2F13-DP12p1) 1.0)
	(= (duration-association-reaction pRb E2F13-DP12 pRb-E2F13-DP12) 1.1)
	(= (duration-association-reaction pRb E2F13p1-DP12p1 pRb-E2F13p1-DP12p1) 1.1)
	(= (duration-association-reaction pRb E2F13p1-DP12 pRb-E2F13p1-DP12) 1.1)
	(= (duration-association-reaction pRb E2F4-DP12 pRb-E2F4-DP12) 1.1)
	(= (duration-association-reaction pRb-Jun c-Fos pRb-Jun-c-Fos) 1.0)
	(= (duration-association-reaction pRb Jun pRb-Jun) 1.1)
	(= (duration-synthesis-reaction pRbp1-AP2-gE-c Ecadherin) 3.6)
	(= (duration-association-reaction pRbp1-AP2 gE-c pRbp1-AP2-gE-c) 1.0)
	(= (duration-association-reaction pRbp1 AP2 pRbp1-AP2) 1.1)
	(= (duration-association-reaction pRbp1 E2F13-DP12p1 pRbp1-E2F13-DP12p1) 1.0)
	(= (duration-association-reaction pRbp1 E2F13-DP12 pRbp1-E2F13-DP12) 0.9)
	(= (duration-association-reaction pRbp1 E2F13p1-DP12p1 pRbp1-E2F13p1-DP12p1) 0.8)
	(= (duration-association-reaction pRbp1 E2F13p1-DP12 pRbp1-E2F13p1-DP12) 1.0)
	(= (duration-association-reaction pRbp1 E2F4-DP12 pRbp1-E2F4-DP12) 1.0)
	(= (duration-association-reaction pRbp1-Jun c-Fos pRbp1-Jun-c-Fos) 0.9)
	(= (duration-association-reaction pRbp1 Jun pRbp1-Jun) 1.1)
	(= (duration-synthesis-reaction pRbp1p2-AP2-gE-c Ecadherin) 3.7)
	(= (duration-association-reaction pRbp1p2-AP2 gE-c pRbp1p2-AP2-gE-c) 1.1)
	(= (duration-association-reaction pRbp1p2 AP2 pRbp1p2-AP2) 1.1)
	(= (duration-association-reaction pRbp1p2-Jun c-Fos pRbp1p2-Jun-c-Fos) 1.0)
	(= (duration-association-reaction pRbp1p2 Jun pRbp1p2-Jun) 0.9)
	(= (duration-synthesis-reaction pRbp2-AP2-gE-c Ecadherin) 4.4)
	(= (duration-association-reaction pRbp2-AP2 gE-c pRbp2-AP2-gE-c) 1.0)
	(= (duration-association-reaction pRbp2 AP2 pRbp2-AP2) 0.9)
	(= (duration-catalyzed-association-reaction pRbp2 cdk46p3-cycDp1 pRbp1p2) 1.7)
	(= (duration-catalyzed-association-reaction pRbp2 cdk46p3-cycD pRbp1p2) 1.8)
	(= (duration-association-reaction pRbp2-Jun c-Fos pRbp2-Jun-c-Fos) 0.9)
	(= (duration-association-reaction pRbp2 Jun pRbp2-Jun) 0.8)
	(= (duration-association-reaction Raf1 p130-E2F4-DP12 Raf1-p130-E2F4-DP12) 1.0)
	(= (duration-association-reaction Raf1 p130-E2F4p1-DP12 Raf1-p130-E2F4p1-DP12) 1.1)
	(= (duration-association-reaction Raf1 p130-E2F5-DP12 Raf1-p130-E2F5-DP12) 1.0)
	(= (duration-association-reaction Raf1 p130-E2F5p1-DP12 Raf1-p130-E2F5p1-DP12) 1.1)
	(= (duration-association-reaction Raf1 pRb-E2F13-DP12p1 Raf1-pRb-E2F13-DP12p1) 1.1)
	(= (duration-association-reaction Raf1 pRb-E2F13-DP12 Raf1-pRb-E2F13-DP12) 1.0)
	(= (duration-association-reaction Raf1 pRb-E2F13p1-DP12p1 Raf1-pRb-E2F13p1-DP12p1) 1.0)
	(= (duration-association-reaction Raf1 pRb-E2F13p1-DP12 Raf1-pRb-E2F13p1-DP12) 0.9)
	(= (duration-association-reaction Raf1 pRb-E2F4-DP12 Raf1-pRb-E2F4-DP12) 0.8)
	(= (duration-association-reaction Raf1 pRbp1-E2F13-DP12p1 Raf1-pRbp1-E2F13-DP12p1) 0.9)
	(= (duration-association-reaction Raf1 pRbp1-E2F13-DP12 Raf1-pRbp1-E2F13-DP12) 0.8)
	(= (duration-association-reaction Raf1 pRbp1-E2F13p1-DP12p1 Raf1-pRbp1-E2F13p1-DP12p1) 0.8)
	(= (duration-association-reaction Raf1 pRbp1-E2F13p1-DP12 Raf1-pRbp1-E2F13p1-DP12) 1.1)
	(= (duration-association-reaction Raf1 pRbp1-E2F4-DP12 Raf1-pRbp1-E2F4-DP12) 0.9)
	(= (duration-association-reaction Raf1 pRbp1-E2F4p1-DP12 Raf1-pRbp1-E2F4p1-DP12) 0.9)
	(= (duration-catalyzed-association-reaction SL1 cdk1p3-cycB SL1p1) 1.8)
	(= (duration-catalyzed-association-reaction Wee1 cdk1p3-cycB Wee1p1) 2.3))

(:goal
	(and
	(preference p0A (>= (+ (available cdk1p3-cycB) (available SL1p1)) 4))
	(preference p0B (>= (+ (available Wee1p1) (available cdk1p3-Gadd45)) 3))
	(preference p0C (>= (+ (available cdk1p3-cks1) (available cdk1p1p3-Gadd45)) 5))
	(preference p0D (>= (+ (available cdk1p1-cks1) (available cdk1p1p3-cks1)) 4))
	(preference p0E (>= (+ (available cdk1-cks1) (available cdk1p1p3-cycB)) 5))
	(preference p0F (>= (+ (available cdk1p1p2p3-cycB) (available Raf1-p130-E2F5-DP12)) 8))
	(preference p0G (>= (+ (available cdk1p2p3-cycB) (available cdk1p2p3)) 7))
	(preference p0H (>= (+ (available cdk1p3) (available cdk2p2-cks1)) 5))
	(preference p0I (>= (+ (available cdk1p1p2p3-Gadd45) (available Raf1-pRbp1-E2F13-DP12)) 6))
	(preference p0J (>= (+ (available cdk1p2p3-cks1) (available cdk1p2p3-Gadd45)) 5))
	(preference p0K (>= (+ (available cdk1-Gadd45) (available pRbp1p2-Jun-c-Fos)) 6))
	(preference p0L (>= (+ (available cdk1p2-cks1) (available cdk1)) 7))
	(preference p0M (>= (+ (available CEBP-pRbp1) (available p16-cdk7p1)) 6))))


(:constraints (and

	(preference p1A (sometime-before (> (available SL1p1) 0) (> (available cdk1p3) 0)))
	(preference p1B (sometime-before (> (available cdk1p1-cks1) 0) (> (available cdk1p1) 0)))
	(preference p1C (sometime-before (> (available cdk1-cks1) 0) (> (available cdk1) 0)))
	(preference p1D (sometime-before (> (available cdk1p2p3-cycB) 0) (> (available cdk1p1p2p3-cycB) 0)))
	(preference p1E (sometime-before (> (available cdk1p3) 0) (> (available cdk1p2) 0)))
	(preference p1F (sometime-before (> (available cdk1p2p3-Gadd45) 0) (> (available cdk7-cycH) 0)))
	(preference p1G (sometime-before (> (available cdk1-Gadd45) 0) (> (available Gadd45) 0)))
	(preference p1H (sometime-before (> (available cdk1) 0) (> (available cdc25Cp1) 0)))

	(preference p1I (always (= (available cdk1p1p3) 0)))
	(preference p1J (always (= (available cdc25Cp1p2) 0)))

	(preference p1K (sometime (> (available pRbp1-E2F13p1-DP12) 0)))
	(preference p1L (sometime-after (> (available pRbp1-E2F13p1-DP12) 0) (> (available p21) 0)))
	(preference p1M (sometime (> (available Jun-c-Fos) 0)))
	(preference p1N (sometime-after (> (available Jun-c-Fos) 0) (> (available pRbp1p2-AP2) 0)))
	(preference p1O (sometime (> (available pRbp1-E2F13-DP12p1) 0)))
	(preference p1P (sometime-after (> (available pRbp1-E2F13-DP12p1) 0) (> (available cdk1p1p2-cks1) 0)))
	(preference p1Q (sometime (> (available Raf1-pRbp1-E2F4p1-DP12) 0)))
	(preference p1R (sometime-after (> (available Raf1-pRbp1-E2F4p1-DP12) 0) (> (available pRbp2-Jun-c-Fos) 0)))
	(preference p1S (sometime (> (available pRbp1-Jun) 0)))
	(preference p1T (sometime-after (> (available pRbp1-Jun) 0) (> (available HDAC1-p130-E2F5-DP12) 0)))))

(:metric minimize (+ (* 1.7 (is-violated p0A))
		     (* 2.0 (is-violated p0B))
		     (* 1.9 (is-violated p0C))
		     (* 1.8 (is-violated p0D))
		     (* 1.8 (is-violated p0E))
		     (* 2.0 (is-violated p0F))
		     (* 1.8 (is-violated p0G))
		     (* 2.0 (is-violated p0H))
		     (* 1.8 (is-violated p0I))
		     (* 1.8 (is-violated p0J))
		     (* 1.7 (is-violated p0K))
		     (* 1.8 (is-violated p0L))
		     (* 1.9 (is-violated p0M))
		     (* 1 (is-violated p1A))
		     (* 1 (is-violated p1B))
		     (* 1 (is-violated p1C))
		     (* 1 (is-violated p1D))
		     (* 1 (is-violated p1E))
		     (* 1 (is-violated p1F))
		     (* 1 (is-violated p1G))
		     (* 1 (is-violated p1H))
		     (* 1 (is-violated p1I))
		     (* 1 (is-violated p1J))
		     (* 1 (is-violated p1K))
		     (* 1 (is-violated p1L))
		     (* 1 (is-violated p1M))
		     (* 1 (is-violated p1N))
		     (* 1 (is-violated p1O))
		     (* 1 (is-violated p1P))
		     (* 1 (is-violated p1Q))
		     (* 1 (is-violated p1R))
		     (* 1 (is-violated p1S))
		     (* 1 (is-violated p1T))
		     (* 0.01 (total-time))
		     (num-subs)))

)
